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Tissue engineering using a combined cell sheet technology and scaffolding approach

Zurina I. M.[1,2,3], Presniakova V. S.[1], Butnaru D.V.[4], Svistunov A. A.[4], Timashev P. S.[1,5,6,7], Rochev Y. A.[1,8]
Acta Biomaterialia
Volume 113, Pages 63-83
Опубликовано: 1 September 2020
Тип ресурса: Статья; Обзор

DOI:10.1016/j.actbio.2020.06.016

Документ://resource.rucml.ru/feml/protected/0000000008R/

Аннотация:
Cell sheet technology has remained quite popular among tissue engineering techniques over the last several years. Meanwhile, there is an apparent trend in modern scientific research towards combining different approaches and strategies. Accordingly, a large body of work has arisen where cell sheets are used not as separate structures, but in combination with scaffolds as supporting constructions. The aim of this review is to analyze the intersection of these two vast areas of tissue engineering described in the literature mainly within the last five years. Some practical and technical details are emphasized to provide information that can be useful in research design and planning. The first part of the paper describes the general issues concerning the use of combined technology, its advantages and limitations in comparison with those of other tissue engineering approaches. Next, the detailed literature analysis of in vivo studies aimed at the regeneration of different tissues is performed. A significant part of this section concerns bone regeneration. In addition to that, other connective tissue structures, including articular cartilage and fibrocartilage, ligaments and tendons, and some soft tissues are discussed.
Statement of significance.This paper describes the intersection of two technologies used in designing of tissue-engineered constructions for regenerative medicine: cell sheets as extracellular matrix-rich structures and supporting scaffolds as essentials in tissue engineering. A large number of reviews are devoted to each of these scientific problems. However, the solution of complex problems of tissue engineering requires an integrated approach that includes both three-dimensional scaffolds and cell sheets. This manuscript serves as a description of advantages and limitations of this method, its use in regeneration of bones, connective tissues and soft tissues and some other details.
Ключевые слова:
Cell sheet; Implantation; Regenerative medicine; Scaffolds; Tissue engineering
CRUCIATE LIGAMENT RECONSTRUCTION; MARROW STROMAL CELLS; PERIODONTAL REGENERATION; TRICALCIUM PHOSPHATE; CHONDROCYTE SHEETS; LOCAL-DELIVERY; BONE COMPOSITE; TRANSPLANTATION; CULTURE; TENDON
[1]Sechenov University.Institute for Regenerative Medicine
[2]Institute of General Pathology and Pathophysiology
[3]Russian Medical Academy of Continuous Professional Education
[4]Sechenov University.Rectorate
[5]Research Center Crystallography and Photonics
[6]N.N. Semenov Institute of Chemical Physics.Department of Polymers and Composites
[7]Lomonosov Moscow State University.Chemistry Department
[8]National University of Ireland Galway.Centre for Research in Medical Devices (CÚRAM)
Zurina I. M. Irina Sechenov University.Institute for Regenerative Medicine|Institute of General Pathology and Pathophysiology|Russian Medical Academy of Continuous Professional Education
Presniakova V. S. Viktoria Sechenov University.Institute for Regenerative Medicine
Butnaru D.V. Denis Victorovich urologist 1978- Sechenov University.Rectorate
Svistunov A. A. Andrey Alekseevich pharmacist Sechenov University.Rectorate
Timashev P. S. Peter Sechenov University.Institute for Regenerative Medicine|Research Center Crystallography and Photonics|N.N. Semenov Institute of Chemical Physics.Department of Polymers and Composites|Lomonosov Moscow State University.Chemistry Department
Rochev Y. A. Yury Sechenov University.Institute for Regenerative Medicine|National University of Ireland Galway.Centre for Research in Medical Devices (CÚRAM)
Зурина И. М. Ирина Михайловна Сеченовский университет.Институт регенеративной медицины|Институт общей патологии и патофизиологии|Российская медицинская академия непрерывного профессионального образования
Преснякова В. С. Виктория Сеченовский университет.Институт регенеративной медицины
Бутнару Д. В. Денис Викторович уролог 1978- Сеченовский Университет.Ректорат
Свистунов А. А. Андрей Алексеевич фармацевт Сеченовский университет.Ректорат
Тимашев П. С. Петр Сергеевич Сеченовский университет.Институт регенеративной медицины|Научно-исследовательский центр кристаллографии и фотоники|Институт химической физики им.Н. Н. Семенова.Кафедра полимеров и композитов|Московский государственный университет им.М. В. Ломоносова.Химический факультет
Рочев Ю. А. Юрий Алексеевич Сеченовский университет.Институт регенеративной медицины|Национальный университет Ирландии Голуэй.Центр исследований в области медицинских приборов
Tissue engineering using a combined cell sheet technology and scaffolding approach
Text visual unmediated
Acta Biomaterialia
Volume 113 Pages 63-83
1 September 2020
ELSEVIER SCI LTD THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
Статья
Обзор
Cell sheet Implantation Regenerative medicine Scaffolds Tissue engineering
CRUCIATE LIGAMENT RECONSTRUCTION MARROW STROMAL CELLS PERIODONTAL REGENERATION TRICALCIUM PHOSPHATE CHONDROCYTE SHEETS LOCAL-DELIVERY BONE COMPOSITE TRANSPLANTATION CULTURE TENDON
Cell sheet technology has remained quite popular among tissue engineering techniques over the last several years. Meanwhile, there is an apparent trend in modern scientific research towards combining different approaches and strategies. Accordingly, a large body of work has arisen where cell sheets are used not as separate structures, but in combination with scaffolds as supporting constructions. The aim of this review is to analyze the intersection of these two vast areas of tissue engineering described in the literature mainly within the last five years. Some practical and technical details are emphasized to provide information that can be useful in research design and planning. The first part of the paper describes the general issues concerning the use of combined technology, its advantages and limitations in comparison with those of other tissue engineering approaches. Next, the detailed literature analysis of in vivo studies aimed at the regeneration of different tissues is performed. A significant part of this section concerns bone regeneration. In addition to that, other connective tissue structures, including articular cartilage and fibrocartilage, ligaments and tendons, and some soft tissues are discussed.
Statement of significance.This paper describes the intersection of two technologies used in designing of tissue-engineered constructions for regenerative medicine: cell sheets as extracellular matrix-rich structures and supporting scaffolds as essentials in tissue engineering. A large number of reviews are devoted to each of these scientific problems. However, the solution of complex problems of tissue engineering requires an integrated approach that includes both three-dimensional scaffolds and cell sheets. This manuscript serves as a description of advantages and limitations of this method, its use in regeneration of bones, connective tissues and soft tissues and some other details.
Унифицированный идентификатор ресурса для цитирования: //repo.rucml.ru/articles/0000000008/