Morphological study of lymphoid organs at early stages of experimental prostate carcinogenesis
Ломшаков А. А., Асташов В. В., Козлов В. И., Рyжакин С. М., Улога М. В., Медянцева Д. А.
Урология
Т. 2019, Вып. 3, С. 89-94
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.18565/urology.2019.3.89-94
Аннотация:
Aim. the aim of our study was to identify of structural transformations in the thymus and lymph nodes at the early stages of the development of an experimental prostate cancer. Materials and methods. Experiments were performed on 60 adult male CBA mice weighing 28-30 g. An experimental model of a prostate cancer was created by inoculating a diluted cell strain of Ehrlich Ascites Carcinoma cells into the prostatic parenchyma through midline laparotomy under ether anesthesia. The animals were divided into three groups of 20 each: 1) control (intact animals) 2) animals on the 5th day of experimental prostate tumor growth and 3) animals on the 18th day of experimental prostate tumor growth. The pathological examination of the prostate, thymus, and pelvic lymph nodes was performed. The selection of structural components and cellular elements in the thymus and lymph nodes was carried out according to the International histological nomenclature. Results. According to the results, there was an
Ключевые слова:
Pelvic lymph nodes; Prostate cancer; Thymus
adult; animal; carcinogenesis; CBA mouse; human; lymph node metastasis; male; mouse; pathology; prostate tumor; Adult; Animals; Carcinogenesis; Humans; Lymphatic Metastasis; Male; Mice; Mice, Inbred CBA; Prostatic Neoplasms
Язык текста: Русский
ISSN: 1728-2985
Ломшаков А. А.
Асташов В. В.
Козлов В. И.
Рyжакин С. М.
Улога М. В.
Медянцева Д. А.
Lomshakov A. A.
Astashov V. V.
Kozlov V. I.
Ryzhakin S. M.
Uloga M. V.
Medyantseva D. A.
Morphological study of lymphoid organs at early stages of experimental prostate carcinogenesis
Текст визуальный непосредственный
Урология
Бионика Медиа
Т. 2019, Вып. 3 С. 89-94
2019
Статья
Pelvic lymph nodes Prostate cancer Thymus
adult animal carcinogenesis CBA mouse human lymph node metastasis male mouse pathology prostate tumor Adult Animals Carcinogenesis Humans Lymphatic Metastasis Male Mice Mice, Inbred CBA Prostatic Neoplasms
Aim. the aim of our study was to identify of structural transformations in the thymus and lymph nodes at the early stages of the development of an experimental prostate cancer. Materials and methods. Experiments were performed on 60 adult male CBA mice weighing 28-30 g. An experimental model of a prostate cancer was created by inoculating a diluted cell strain of Ehrlich Ascites Carcinoma cells into the prostatic parenchyma through midline laparotomy under ether anesthesia. The animals were divided into three groups of 20 each: 1) control (intact animals) 2) animals on the 5th day of experimental prostate tumor growth and 3) animals on the 18th day of experimental prostate tumor growth. The pathological examination of the prostate, thymus, and pelvic lymph nodes was performed. The selection of structural components and cellular elements in the thymus and lymph nodes was carried out according to the International histological nomenclature. Results. According to the results, there was an