Psychological stress and rheumatoid arthritis - Interference of pathogenetic mechanisms
Туаева Н. О., Носырев А. Е., Ренаудинеау Y., Арлеевскайа М. И.
Научно-практическая ревматология
Т. 57, Вып. 1, С. 83-90
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.14412/1995-4484-2019-83-90
Аннотация:
Molecular mechanisms of development of normal and pathological neuroendocrine and immune adaptive response to psychological (mental) stress are analyzed considering its possible provoking role in the development of rheumatoid arthritis (RA). A detailed analysis reveals the synergism of mechanisms that provoke the development of pathological anti-stress adaptive response and RA. It is possible that in persons at risk of developing RA minimal and unobtrusive for the individual stressful situations, periodically provoking prolonged production of pro-inflammatory cytokines, can, finally, lead to the development of rheumatic disease. © 2019 Ima-Press Publishing House. All rights reserved.
Ключевые слова:
Allostasis; Distress; Eustress; Psychological stress; Rheumatoid arthritis
Язык текста: Русский
ISSN: 1995-4492
Туаева Н. О. Наталья Олеговна 1976-
Носырев А. Е. Александр Евгеньевич 1958-
Ренаудинеау Y.
Арлеевскайа М. И.
Tuaeva N. O. Natal`ya Olegovna 1976-
Nosy'rev A. E. Aleksandr Evgenyevich 1958-
Renaudineau Y.
Arleevskaya M. I.
Psychological stress and rheumatoid arthritis - Interference of pathogenetic mechanisms
Текст визуальный непосредственный
Научно-практическая ревматология
ИМА-Пресс
Т. 57, Вып. 1 С. 83-90
2019
Статья
Allostasis Distress Eustress Psychological stress Rheumatoid arthritis
Molecular mechanisms of development of normal and pathological neuroendocrine and immune adaptive response to psychological (mental) stress are analyzed considering its possible provoking role in the development of rheumatoid arthritis (RA). A detailed analysis reveals the synergism of mechanisms that provoke the development of pathological anti-stress adaptive response and RA. It is possible that in persons at risk of developing RA minimal and unobtrusive for the individual stressful situations, periodically provoking prolonged production of pro-inflammatory cytokines, can, finally, lead to the development of rheumatic disease. © 2019 Ima-Press Publishing House. All rights reserved.