Аннотация:
Currently, there has been a progressive increase in prevalence of one of the most common diffuse chronic liver diseases - non-alcoholic fatty liver disease (NAFLD). Assessment of the stages of liver fibrosis and steatosis is prognostically significant in diagnosis of NAFLD. Routine diagnostic methods are either not able to accurately assess the severity of fibrosis and steatosis (ultrasound, laboratory tests), or cannot be used as a simple screening tool (liver biopsy) due to such limitations as invasiveness, dependence on pathologist qualification, high cost, and limited region of interest. Over the last two decades, the great progress has been made in non-invasive visualization of pathological changes in liver diseases. In this review, we examined the diagnostic characteristics of the most widely used non-invasive imaging methods in clinical practice, available for quantitative determination of fat and fibrosis in the liver: transient elastography with controlled attenuation paramete
Ключевые слова:
Acoustic radiation force impulse; Elastography; Liver fibrosis; Nonalcoholic fatty liver disease
acoustic radiation force impulse imaging; chronic liver disease; diagnostic accuracy; elastography; human; intermethod comparison; liver fibrosis; nonalcoholic fatty liver; Review; sensitivity and specificity; shear wave elastography; transient elastography
Широкова Е. Н. Елена Николаевна 1965-
Павлов Ч. С. Чавдар Савов 1967-
Карасева А. Д.
Алиева А. М.
Седова А. В. Алла Владимировна 1977-
Ивашкин В. Т. Владимир Трофимович 1939-
Shirokova E. N. Elena Nikolaevna 1965-
Pavlov Ch. S. Chavdar Savov 1967-
Karaseva A. D.
Alieva A. M.
Sedova A. V. Alla Vladimirovna 1977-
Ivashkin V. T. Vladimir Trofimovich 1939-
Elastography in the diagnosis of non-alcoholic fatty liver disease
Текст визуальный непосредственный
Вестник Российской академии медицинских наук
Издательство "Педиатръ"
Т. 74, Вып. 1 С. 5-13
2019
Обзор
Acoustic radiation force impulse Elastography Liver fibrosis Nonalcoholic fatty liver disease
acoustic radiation force impulse imaging chronic liver disease diagnostic accuracy elastography human intermethod comparison liver fibrosis nonalcoholic fatty liver Review sensitivity and specificity shear wave elastography transient elastography
Currently, there has been a progressive increase in prevalence of one of the most common diffuse chronic liver diseases - non-alcoholic fatty liver disease (NAFLD). Assessment of the stages of liver fibrosis and steatosis is prognostically significant in diagnosis of NAFLD. Routine diagnostic methods are either not able to accurately assess the severity of fibrosis and steatosis (ultrasound, laboratory tests), or cannot be used as a simple screening tool (liver biopsy) due to such limitations as invasiveness, dependence on pathologist qualification, high cost, and limited region of interest. Over the last two decades, the great progress has been made in non-invasive visualization of pathological changes in liver diseases. In this review, we examined the diagnostic characteristics of the most widely used non-invasive imaging methods in clinical practice, available for quantitative determination of fat and fibrosis in the liver: transient elastography with controlled attenuation paramete