Аннотация:
Objective: A considerable proportion of the population due to both economic reasons and traditions appear to be experiencing chronic deficit in micronutrients, which may be deteriorated on the background of drug therapy being performed. The purpose of our study was to optimize pharmacotherapy of patients with first-ever prescribed diuretic-containing combined therapy for arterial hypertension (AH) by means of adding a vitamin-mineral complex. Method: To determine B-group vitamins (thiamine, riboflavin, pyridoxine) in blood plasma by means of high-performance liquid chromatography (HPLC) and, on achieving the target values of arterial pressure (AP), to analyse the patients’ quality of life by means of such neuropsychological tests as the General Health Questionnaire – 36 (GHQ-36) and WAM (wellbeing, activity, mood) questionnaire. Results: The group of patients receiving antihypertensive therapy alone demonstrated a decrease in blood plasma thiamine, riboflavin and pyridoxine from 34.5±4
Shikh E. V. Evgeniya Valeryevna 1962-
Lapidus N. I. Natal`ya Il`inichna 1972-
Tyazhel`nikov A. A. Andrej Aleksandrovich 1975-
Karaulov A. V. Aleksandr Viktorovich 1953-
Drozdov V. N. Vladimir Nikolaevich 1963-
Trukhin I. V. Ivan Viktorovich 1994-
Ших Е. В. Евгения Валерьевна 1962-
Лапидус Н. И. Наталья Ильинична 1972-
Тяжельников А. А. Андрей Александрович 1975-
Караулов А. В. Александр Викторович 1953-
Дроздов В. Н. Владимир Николаевич 1963-
Трухин И. В. Иван Викторович 1994-
Effect of vitamin-mineral complexes on quality of life of patients with arterial hypertension
Текст визуальный непосредственный
Electronic Journal of General Medicine
Modestum Ltd.
Vol.15, Issue4
2018
Статья
Arterial hypertension Diuretics Pharmacotherapy Vitamins
Objective: A considerable proportion of the population due to both economic reasons and traditions appear to be experiencing chronic deficit in micronutrients, which may be deteriorated on the background of drug therapy being performed. The purpose of our study was to optimize pharmacotherapy of patients with first-ever prescribed diuretic-containing combined therapy for arterial hypertension (AH) by means of adding a vitamin-mineral complex. Method: To determine B-group vitamins (thiamine, riboflavin, pyridoxine) in blood plasma by means of high-performance liquid chromatography (HPLC) and, on achieving the target values of arterial pressure (AP), to analyse the patients’ quality of life by means of such neuropsychological tests as the General Health Questionnaire – 36 (GHQ-36) and WAM (wellbeing, activity, mood) questionnaire. Results: The group of patients receiving antihypertensive therapy alone demonstrated a decrease in blood plasma thiamine, riboflavin and pyridoxine from 34.5±4