Arterial spin labeling in assessing regional cerebral blood flow in patients with Alzheimer's disease
Меркуловам С., Солодовников В. И., Коберская Н. Н., Перепелова Е. М., Синицын В. Е., Гридин В. Н., Яхнон Н.
Неврологический журнал
Т. 23, Вып. 6, С. 290-298
Опубликовано: 2018
Тип ресурса: Статья
DOI:10.18821/1560-9545-2018-23-6-290-298
Аннотация:
Introduction. Alzheimer's disease (AD) is the most common neurodegenerathe disease in the population. Often, patients with AD have a combined brain lesion of vascular etiology (cerebral microangiopathy). Arterial blood spin labeling (ASL - Arterial spin labeling) is one of the most modem and promising methods for quantifying cerebral perfusion in patients with AD. Objective. To assess regional cerebral blood flow (CBF) using the ASL method in patients with AD with chronic cerebral ischemia - cerebral microangiopathy (CMA) and without it. Material and methods. A group of 20patients (mean age 66 ± 10 years), consisting of 11 patients with AD without CAIA and 9patients with AD with CMA, was examined. The study was conducted on a Siemens Magnetom Skyra magnetic resonance imaging scanner with a magnetic field induction of3T. The examination protocol included an impulse sequence of arterial blood spin labeling. Using the software for postprocessing data processing Olea Medical Sphere 3.0, th
Ключевые слова:
Alzheimer's disease; Arterial spin labeling; Dementia; Magnetic resonance imaging; Microangiopathy; Non- contrast magnetic resonance perfusion
Язык текста: Русский
ISSN: 2413-0699
Меркуловам С.
Солодовников В. И.
Коберская Н. Н. Надежда Николаевна 1969-
Перепелова Е. М. Елена Михайловна 1954-
Синицын В. Е. Валентин Евгеньевич 0001-
Гридин В. Н.
Яхнон Н.
Merkulovam S.
Solodovnikov V. I.
Koberskaya N. N. Nadezhda Nikolaevna 1969-
Perepelova E. M. Elena Mikhaylovna 1954-
Sinitsy'n V. E. Valentin Evgenyevich 0001-
Gridin V. N.
Yakhnon N.
Arterial spin labeling in assessing regional cerebral blood flow in patients with Alzheimer's disease
Текст визуальный непосредственный
Неврологический журнал
Издательство "Медицина"
Т. 23, Вып. 6 С. 290-298
2018
Статья
Alzheimer's disease Arterial spin labeling Dementia Magnetic resonance imaging Microangiopathy Non- contrast magnetic resonance perfusion
Introduction. Alzheimer's disease (AD) is the most common neurodegenerathe disease in the population. Often, patients with AD have a combined brain lesion of vascular etiology (cerebral microangiopathy). Arterial blood spin labeling (ASL - Arterial spin labeling) is one of the most modem and promising methods for quantifying cerebral perfusion in patients with AD. Objective. To assess regional cerebral blood flow (CBF) using the ASL method in patients with AD with chronic cerebral ischemia - cerebral microangiopathy (CMA) and without it. Material and methods. A group of 20patients (mean age 66 ± 10 years), consisting of 11 patients with AD without CAIA and 9patients with AD with CMA, was examined. The study was conducted on a Siemens Magnetom Skyra magnetic resonance imaging scanner with a magnetic field induction of3T. The examination protocol included an impulse sequence of arterial blood spin labeling. Using the software for postprocessing data processing Olea Medical Sphere 3.0, th