Hemorrhagic fever with renal syndrome group outbreak caused by Sochi virus [аНаЛИЗ ГРУППОВОЙ ВСПЫШкИ ГЕМОРРаГИЧЕСкОЙ ЛИХОРаДкИ С ПОЧЕЧНЫМ...
Дзагурова Т. К., Ишмухаметов А. А., Бахтина В. А., Морозов В. Г., Баловнева М. В., Курашова С. С., Клемпа Б., Кругер Д., Ткаченко Е. А.
Вопросы вирусологии
Т. 64, Вып. 1, С. 36-41
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.18821/0507-4088-2019-64-1-36-41
Аннотация:
Introduction. Hemorrhagic fever with renal syndrome (HFRS) occupies a leading place among natural focal human diseases in the Russian Federation. Sporadic incidence of HFRS-Sochi has been annually recorded in the Krasnodar Territory since 2000. The group outbreak of the HFRS-Sochi was first registered in Gelendzhik in the fall of 2013. Material and methods. Serological methods were used: indirect immunofluorescence, enzyme immunoassay, FRNT in Vero cells, and methods for the viral RNA detection: PCR and RT-PCR. Results. Data of clinical, epidemiological, immunological and molecular studies of 3 out of 4 cases in HFRS-Sochi outbreak are presented. Severity of the disease correlated with early gastrointestinal disorders appearance. Patient MA gastrointestinal disorders were joined on day 3 of a fever. Clinical and laboratory studies revealed signs of kidneys, liver, pancreas damage, bilateral hydrothorax, bilateral polysegmental pneumonia and polyneuropathy. As a result of long-term trea
Ключевые слова:
Black-Sea field mouse; Hantaviruses; Hemorrhagic fever with renal syndrome; Sochi virus
virus antigen; virus RNA; virus RNA; animal tissue; antigen detection; Article; clinical article; disease association; disease severity; epidemic; fever; gastrointestinal disease; gastrointestinal symptom; Hantavirus; hemorrhagic fever with renal syndrome; hospitalization; human; human tissue; hydrothorax; kidney injury; liver injury; long term care; lung parenchyma; mouse; nonhuman; pancreas injury; pneumonia; polyneuropathy; sochi virus; virus; adult; animal; blood; case report; Chlorocebus aethiops; female; Hantavirus; hemorrhagic fever with renal syndrome; incidence; isolation and purification; male; metabolism; middle aged; murine; Russian Federation; Vero cell line; Adult; Animals; Chlorocebus aethiops; Disease Outbreaks; Female; Hantavirus; Hemorrhagic Fever with Renal Syndrome; Humans; Incidence; Male; Middle Aged; Murinae; RNA, Viral; Russia; Vero Cells
Язык текста: Русский
ISSN: 2411-2097
Дзагурова Т. К.
Ишмухаметов А. А. Айдар Айратович 1957-
Бахтина В. А.
Морозов В. Г.
Баловнева М. В.
Курашова С. С.
Клемпа Б.
Кругер Д.
Ткаченко Е. А.
Dzagurova T. K.
Ishmukhametov A. A. Aydar Ayratovich 1957-
Bakhtina V. A.
Morozov V. G.
Balovneva M. V.
Kurashova S. S.
Klempa B.
Kruger D.
Tkachenko E. A.
Hemorrhagic fever with renal syndrome group outbreak caused by Sochi virus [аНаЛИЗ ГРУППОВОЙ ВСПЫШкИ ГЕМОРРаГИЧЕСкОЙ ЛИХОРаДкИ С ПОЧЕЧНЫМ СИНДРОМОМ, ВЫЗВаННОЙ ВИРУСОМ СОЧИ]
Hemorrhagic fever with renal syndrome group outbreak caused by Sochi virus [аНаЛИЗ ГРУППОВОЙ ВСПЫШкИ ГЕМОРРаГИЧЕСкОЙ ЛИХОРаДкИ С ПОЧЕЧНЫМ...
Текст визуальный непосредственный
Вопросы вирусологии
Издательство "Медицина"
Т. 64, Вып. 1 С. 36-41
2019
Статья
Black-Sea field mouse Hantaviruses Hemorrhagic fever with renal syndrome Sochi virus
virus antigen virus RNA virus RNA animal tissue antigen detection Article clinical article disease association disease severity epidemic fever gastrointestinal disease gastrointestinal symptom Hantavirus hemorrhagic fever with renal syndrome hospitalization human human tissue hydrothorax kidney injury liver injury long term care lung parenchyma mouse nonhuman pancreas injury pneumonia polyneuropathy sochi virus virus adult animal blood case report Chlorocebus aethiops female Hantavirus hemorrhagic fever with renal syndrome incidence isolation and purification male metabolism middle aged murine Russian Federation Vero cell line Adult Animals Chlorocebus aethiops Disease Outbreaks Female Hantavirus Hemorrhagic Fever with Renal Syndrome Humans Incidence Male Middle Aged Murinae RNA, Viral Russia Vero Cells
Introduction. Hemorrhagic fever with renal syndrome (HFRS) occupies a leading place among natural focal human diseases in the Russian Federation. Sporadic incidence of HFRS-Sochi has been annually recorded in the Krasnodar Territory since 2000. The group outbreak of the HFRS-Sochi was first registered in Gelendzhik in the fall of 2013. Material and methods. Serological methods were used: indirect immunofluorescence, enzyme immunoassay, FRNT in Vero cells, and methods for the viral RNA detection: PCR and RT-PCR. Results. Data of clinical, epidemiological, immunological and molecular studies of 3 out of 4 cases in HFRS-Sochi outbreak are presented. Severity of the disease correlated with early gastrointestinal disorders appearance. Patient MA gastrointestinal disorders were joined on day 3 of a fever. Clinical and laboratory studies revealed signs of kidneys, liver, pancreas damage, bilateral hydrothorax, bilateral polysegmental pneumonia and polyneuropathy. As a result of long-term trea