Аннотация:
The primary autoimmune liver diseases conventionally include primary biliary cholangitis, primary sclerosing cholangitis and autoimmune hepatitis. Despite of primary autoimmune affection of different parts of the hepatobiliary system, in the recent decades, a lot of data has emerged indicating the presence of extrahepatic manifestations of these diseases, in particular, lung lesions, such as nodular and interstitial changes with possible progression and development of fibrosis and respiratory failure. In case of lungs disease, both pulmonary parenchyma and lung vessels, pleura, and intrathoracic lymph nodes can be involved. The most sensitive and specific procedure to assess the extent of the lung lesions and their evolution is high-resolution computed tomography. Due to the possibility of long-term asymptomatic course of the pulmonary disease with development of irreversible changes in patients with autoimmune liver diseases, it seems reasonable to conduct screening studies aimed at e
Ключевые слова:
Autoimmune hepatitis; Interstitial lung disease; Primary biliary cholangitis; Primary sclerosing cholangitis
autoimmune hepatitis; biliary cirrhosis; complication; diagnostic imaging; human; immunology; interstitial lung disease; sclerosing cholangitis; x-ray computed tomography; Cholangitis, Sclerosing; Hepatitis, Autoimmune; Humans; Liver Cirrhosis, Biliary; Lung Diseases, Interstitial; Tomography, X-Ray Computed
Акулкина Л. А. Лариса Анатольевна 1992-
Бровко М. Ю. Михаил Юрьевич 1984-
Шоломова В. И. Виктория Игоревна 1987-
Розина Т. П. Тэона Павловна 1974-
Янакайева А. С.
Французевич Л. Y.
Лебедева М. В. Марина Валерьевна 1966-
Фомин В. В. Виктор Викторович 1978-
Akulkina L. A. Larisa Anatolyevna 1992-
Brovko M. Yu. Mikhail Yuryevich 1984-
Sholomova V. I. Viktoriya Igorevna 1987-
Rozina T. P. Te`ona Pavlovna 1974-
Yanakayeva A. S.
Frantsuzevich L. Y.
Lebedeva M. V. Marina Valeryevna 1966-
Fomin V. V. Viktor Viktorovich 1978-
Variety of lung involvement in autoimmune liver diseases
Текст визуальный непосредственный
Терапевтический архив
Медицинское маркетинговое агентство "МедиаМедика"
Т. 90, Вып. 8 С. 107-112
2018
Статья
Autoimmune hepatitis Interstitial lung disease Primary biliary cholangitis Primary sclerosing cholangitis
autoimmune hepatitis biliary cirrhosis complication diagnostic imaging human immunology interstitial lung disease sclerosing cholangitis x-ray computed tomography Cholangitis, Sclerosing Hepatitis, Autoimmune Humans Liver Cirrhosis, Biliary Lung Diseases, Interstitial Tomography, X-Ray Computed
The primary autoimmune liver diseases conventionally include primary biliary cholangitis, primary sclerosing cholangitis and autoimmune hepatitis. Despite of primary autoimmune affection of different parts of the hepatobiliary system, in the recent decades, a lot of data has emerged indicating the presence of extrahepatic manifestations of these diseases, in particular, lung lesions, such as nodular and interstitial changes with possible progression and development of fibrosis and respiratory failure. In case of lungs disease, both pulmonary parenchyma and lung vessels, pleura, and intrathoracic lymph nodes can be involved. The most sensitive and specific procedure to assess the extent of the lung lesions and their evolution is high-resolution computed tomography. Due to the possibility of long-term asymptomatic course of the pulmonary disease with development of irreversible changes in patients with autoimmune liver diseases, it seems reasonable to conduct screening studies aimed at e