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Microemulsions as Potential Bases for Formulating Modern Transdermal Therapeutics

Gil`deeva G. N., Yurkov V. I.
Pharmaceutical Chemistry Journal
Vol.52, Issue6, P. 550-552
Опубликовано: 2018
Тип ресурса: Статья

DOI:10.1007/s11094-018-1858-6

Аннотация:
Promising directions for the discovery of universal carriers for active pharmaceutical ingredients (APIs) are reviewed. Transdermal delivery of the APIs in medicines is attracting increasing attention from designers of drug formulations. A transdermal therapeutic system (TTS) is a dosage form for external use as controlled-release patches or films. TTSs are classified depending on the mode of API incorporation into several basic types such as reservoir, adhesive, matrix, and microreservoir. Methods for developing TTSs based on microemulsions are described in the review. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.
Ключевые слова:
emulsions; transdermal delivery; transdermal therapeutic systems
absorption; Article; drug diffusion; electric conductivity; flocculation; microemulsion; neutron scattering; nuclear magnetic resonance spectroscopy; particle size; physical chemistry; polarization microscopy; sedimentation; skin permeability; surface area; viscosity
Язык текста: Английский
ISSN: 1573-9031
Gil`deeva G. N. Ge`liya Nyazy'fovna 1967-
Yurkov V. I.
Гильдеева Г. Н. Гэлия Нязыфовна 1967-
Юрков В. И.
Microemulsions as Potential Bases for Formulating Modern Transdermal Therapeutics
Текст визуальный непосредственный
Pharmaceutical Chemistry Journal
Springer New York Consultants Bureau
Vol.52, Issue6 P. 550-552
2018
Статья
emulsions transdermal delivery transdermal therapeutic systems
absorption Article drug diffusion electric conductivity flocculation microemulsion neutron scattering nuclear magnetic resonance spectroscopy particle size physical chemistry polarization microscopy sedimentation skin permeability surface area viscosity
Promising directions for the discovery of universal carriers for active pharmaceutical ingredients (APIs) are reviewed. Transdermal delivery of the APIs in medicines is attracting increasing attention from designers of drug formulations. A transdermal therapeutic system (TTS) is a dosage form for external use as controlled-release patches or films. TTSs are classified depending on the mode of API incorporation into several basic types such as reservoir, adhesive, matrix, and microreservoir. Methods for developing TTSs based on microemulsions are described in the review. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.