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Impact of atrial fibrillation on the rate of mild cognitive impairment in the elderly

Krupenin P., Gabitova M. A., Bordovsky S., Kirichuk Y., Napalkov D. A., Preobrazhenskaya I. S., Sokolova A. A.
Journal of the Neurological Sciences
Vol.394, P. 75-77
Опубликовано: 2018
Тип ресурса: Статья

DOI:10.1016/j.jns.2018.08.023

Аннотация:
Mild cognitive impairment (MCI) in patients with cardiovascular risks is a transitional state to vascular dementia but which still has a possibility of being managed. The objectives of this study were to assess the impact of atrial fibrillation (AF) on cognitive performances in the elderly in comparison with similar cardiovascular risks. One hundred unselected patients were included in AF+ and AF- groups. Patients with prodromal Alzheimer disease as shown by semantic cueing test, and those suffering from major cognitive decline according to DSM 5 criteria were evaluated separately from those patients analysed for vascular cognitive impairment. MCI was distinguished with the help of the Montreal cognitive assessment and the mood status was studied with the geriatric depression scale. AF+ patients predominantly had paroxysmal type of AF with a mean duration of 6.3 years, with 77[%] of the patients being on anticoagulation. AF- patients had arterial hypertension. Prevalence of MCI was signi
Ключевые слова:
Atrial fibrillation; Hypertension; Mild cognitive impairment; Vascular cognitive impairment
aged; Alzheimer disease; anticoagulation; antihypertensive therapy; Article; atrial fibrillation; cardiovascular risk; cholesterol blood level; clinical evaluation; cognition; cognitive defect; daily life activity; diabetes mellitus; DSM-5; female; Geriatric Depression Scale; heart infarction; human; hypertension; major clinical study; male; mild cognitive impairment; Montreal cognitive assessment; prevalence; priority journal; aging; atrial fibrillation; blood pressure; cognitive defect; complication; depression; geriatric assessment; neuropsychological test; physiology; very elderly; anticoagulant agent; Aged; Aged, 80 and over; Aging; Anticoagulants; Atrial Fibrillation; Blood Pressure; Cognitive Dysfunction; Depression; Female; Geriatric Assessment; Humans; Male; Neuropsychological Tests
Язык текста: Английский
ISSN: 1878-5883
Krupenin P.
Gabitova M. A. Mariya Aleksandrovna 1991-
Bordovsky S.
Kirichuk Y.
Napalkov D. A. Dmitrij Aleksandrovich 1975-
Preobrazhenskaya I. S. Irina Sergeevna 1970-
Sokolova A. A. Anastasiya Andreevna 1983-
Крупенин П.
Габитова М. А. Мария Александровна 1991-
Бордовскy С.
Киричук Y.
Напалков Д. А. Дмитрий Александрович 1975-
Преображенская И. С. Ирина Сергеевна 1970-
Соколова А. А. Анастасия Андреевна 1983-
Impact of atrial fibrillation on the rate of mild cognitive impairment in the elderly
Текст визуальный непосредственный
Journal of the Neurological Sciences
Elsevier Science Publisher B.V.
Vol.394 P. 75-77
2018
Статья
Atrial fibrillation Hypertension Mild cognitive impairment Vascular cognitive impairment
aged Alzheimer disease anticoagulation antihypertensive therapy Article atrial fibrillation cardiovascular risk cholesterol blood level clinical evaluation cognition cognitive defect daily life activity diabetes mellitus DSM-5 female Geriatric Depression Scale heart infarction human hypertension major clinical study male mild cognitive impairment Montreal cognitive assessment prevalence priority journal aging atrial fibrillation blood pressure cognitive defect complication depression geriatric assessment neuropsychological test physiology very elderly anticoagulant agent Aged Aged, 80 and over Aging Anticoagulants Atrial Fibrillation Blood Pressure Cognitive Dysfunction Depression Female Geriatric Assessment Humans Male Neuropsychological Tests
Mild cognitive impairment (MCI) in patients with cardiovascular risks is a transitional state to vascular dementia but which still has a possibility of being managed. The objectives of this study were to assess the impact of atrial fibrillation (AF) on cognitive performances in the elderly in comparison with similar cardiovascular risks. One hundred unselected patients were included in AF+ and AF- groups. Patients with prodromal Alzheimer disease as shown by semantic cueing test, and those suffering from major cognitive decline according to DSM 5 criteria were evaluated separately from those patients analysed for vascular cognitive impairment. MCI was distinguished with the help of the Montreal cognitive assessment and the mood status was studied with the geriatric depression scale. AF+ patients predominantly had paroxysmal type of AF with a mean duration of 6.3 years, with 77[%] of the patients being on anticoagulation. AF- patients had arterial hypertension. Prevalence of MCI was signi