Аннотация:
The association of latent toxoplasmosis with mental disorders in general and with schizophrenia in particular was noticed in the mid-1950s. In subsequent years, the role of Toxoplasma gondii was established based on its ability to survive for long periods of time in the nerve cells of the brain. The acute manifestations of the infection include psychopathic symptoms resembling those of schizophrenia. In the former USSR, and in other parts of the world, a number of studies were performed with respect to the association of latent toxoplasmosis and schizophrenia. However, with the dissolution of the USSR at the beginning of the 1990s, studies on the subject were halted due to financial problems and have resumed only recently. The reasons for the resumption of such studies in contemporary Russia are related to the progressively increasing incidence of schizophrenia over the last 25-30 years in the country. According to official data, approximately 550 000 persons reported suffering from th
Stepanova E. V. Ekaterina Viktorovna 1983-
Kondrashin A. V. Anatolij Viktorovich 1940-
Sergiev V. P. Vladimir Petrovich 1943-
Morozova L. F. Lola Farmonovna 1975-
Turbabina N. A. Natal`ya Aleksandrovna 1981-
Maksimova M. S. Mariya Sergeevna 1987-
Romanov D. V. Dmitrij Vladimirovich 1980-
Kinkul`kina M. A. Marina Arkadyevna 1966-
Lazareva A. V.
Morozov E. N. Evgenij Nikolaevich 1973-
Степанова Е. В. Екатерина Викторовна 1983-
Кондрашин А. В. Анатолий Викторович 1940-
Сергиев В. П. Владимир Петрович 1943-
Морозова Л. Ф. Лола Фармоновна 1975-
Турбабина Н. А. Наталья Александровна 1981-
Максимова М. С. Мария Сергеевна 1987-
Романов Д. В. Дмитрий Владимирович 1980-
Кинкулькина М. А. Марина Аркадьевна 1966-
Лазарева А. В.
Морозов Е. Н. Евгений Николаевич 1973-
Toxoplasmosis and mental disorders in the Russian Federation (with special reference to schizophrenia)
Текст визуальный непосредственный
PLoS ONE
Vol.14, Issue7 Num.e0219454
2019
Статья
immunoglobulin G immunoglobulin M adult Article controlled study disease association disease burden female human major clinical study male morbidity Russian Federation schizophrenia serology seroprevalence toxoplasmosis adolescent blood brain complication enzyme linked immunosorbent assay immunology mental disease middle aged nerve cell pathogenicity pathology schizophrenia seroepidemiology Toxoplasma toxoplasmosis young adult Adolescent Adult Brain Enzyme-Linked Immunosorbent Assay Female Humans Male Mental Disorders Middle Aged Moscow Neurons Russia Schizophrenia Seroepidemiologic Studies Toxoplasma Toxoplasmosis Young Adult
The association of latent toxoplasmosis with mental disorders in general and with schizophrenia in particular was noticed in the mid-1950s. In subsequent years, the role of Toxoplasma gondii was established based on its ability to survive for long periods of time in the nerve cells of the brain. The acute manifestations of the infection include psychopathic symptoms resembling those of schizophrenia. In the former USSR, and in other parts of the world, a number of studies were performed with respect to the association of latent toxoplasmosis and schizophrenia. However, with the dissolution of the USSR at the beginning of the 1990s, studies on the subject were halted due to financial problems and have resumed only recently. The reasons for the resumption of such studies in contemporary Russia are related to the progressively increasing incidence of schizophrenia over the last 25-30 years in the country. According to official data, approximately 550 000 persons reported suffering from th