Correlations between parameters of central hemodynamics and cytokine profile in chronic kidney disease in combination with cerebrovascular diseases
Муркамилов И. Т., Сабиров И. С., Фомин В. В., Муркамилова З. А., Сабирова А. И., Цои Л. Г., Аитбаев К. А., Редйапова Н. А., Юсупов Ф. А.
Журнал неврологии и психиатрии им. C.C. Корсакова
Т. 119, Вып. 6, С. 65-71
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.17116/jnevro201911906165
Аннотация:
Objective. To study the relationship between central hemodynamics and arterial stiffness indicators with cystatin C, tumor necrosis factor-alpha (TNF-alpha) and interleukin-(IL)-10 in patients with chronic kidney disease (CKD) in combination with cerebrovascular diseases (CEV). Material and methods. One hundred and twenty patients, aged from 19 to 81 years, with signs of chronic renal dysfunction, including 73 with CKD (1st group) and 47 with CKD in combination with CEH (group 2), were examined. «AngioScan» (Russia) was used to study indices of arterial rigidity. Blood plasma concentrations of TNF-alpha, IL-10 and cystatin C were determined by the enzyme immunoassay. Results. There is a significant increase (p<0.05) in the systolic, diastolic, central levels of arterial pressure, augmentation index, the index of increase at a pulse rate of 75 per min, the age index, the age of the vascular system and cystatin C content in the patients with CKD in combination with CEV compared to the pa
Ключевые слова:
Augmentation index; Cerebrovascular diseases; Chronic kidney disease; Cystatin c; Cytokines; Glomerular filtration rate
cystatin C; interleukin 10; tumor necrosis factor; adult; aged; arterial stiffness; arterial stiffness index; Article; augmentation index; blood level; cardiovascular system; cerebrovascular disease; chronic kidney failure; cytokine production; diastolic blood pressure; enzyme immunoassay; glomerulus filtration rate; hemodynamics; human; major clinical study; pulse rate; systolic blood pressure; arterial stiffness; complication; middle aged; very elderly; young adult; Adult; Aged; Aged, 80 and over; Cerebrovascular Disorders; Hemodynamics; Humans; Middle Aged; Renal Insufficiency, Chronic; Vascular Stiffness; Young Adult
Язык текста: Русский
ISSN: 2309-4729
Муркамилов И. Т.
Сабиров И. С.
Фомин В. В. Виктор Викторович 1978-
Муркамилова З. А.
Сабирова А. И.
Цои Л. Г.
Аитбаев К. А.
Редйапова Н. А.
Юсупов Ф. А.
Murkamilov I. T.
Sabirov I. S.
Fomin V. V. Viktor Viktorovich 1978-
Murkamilova Z. A.
Sabirova A. I.
Tsoi L. G.
Aitbaev K. A.
Redjapova N. A.
Yusupov F. A.
Correlations between parameters of central hemodynamics and cytokine profile in chronic kidney disease in combination with cerebrovascular diseases
Текст визуальный непосредственный
Журнал неврологии и психиатрии им. C.C. Корсакова
Издательство Медиа Сфера
Т. 119, Вып. 6 С. 65-71
2019
Статья
Augmentation index Cerebrovascular diseases Chronic kidney disease Cystatin c Cytokines Glomerular filtration rate
cystatin C interleukin 10 tumor necrosis factor adult aged arterial stiffness arterial stiffness index Article augmentation index blood level cardiovascular system cerebrovascular disease chronic kidney failure cytokine production diastolic blood pressure enzyme immunoassay glomerulus filtration rate hemodynamics human major clinical study pulse rate systolic blood pressure arterial stiffness complication middle aged very elderly young adult Adult Aged Aged, 80 and over Cerebrovascular Disorders Hemodynamics Humans Middle Aged Renal Insufficiency, Chronic Vascular Stiffness Young Adult
Objective. To study the relationship between central hemodynamics and arterial stiffness indicators with cystatin C, tumor necrosis factor-alpha (TNF-alpha) and interleukin-(IL)-10 in patients with chronic kidney disease (CKD) in combination with cerebrovascular diseases (CEV). Material and methods. One hundred and twenty patients, aged from 19 to 81 years, with signs of chronic renal dysfunction, including 73 with CKD (1st group) and 47 with CKD in combination with CEH (group 2), were examined. «AngioScan» (Russia) was used to study indices of arterial rigidity. Blood plasma concentrations of TNF-alpha, IL-10 and cystatin C were determined by the enzyme immunoassay. Results. There is a significant increase (p<0.05) in the systolic, diastolic, central levels of arterial pressure, augmentation index, the index of increase at a pulse rate of 75 per min, the age index, the age of the vascular system and cystatin C content in the patients with CKD in combination with CEV compared to the pa