Symptomatic and silent cerebral ischemia (detected on MRI) in patients with type 2 diabetes mellitus after carotid revascularization procedures...
Танашян М. М., Антонова К. В., Медведев Р. Б., Скрyлев С. И., Кротенкова М. В., Романцова Т. И.
Сахарный диабет
Т. 22, Вып. 1, С. 14-24
Опубликовано: 2019
Тип ресурса: Статья
Аннотация:
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a significant independent risk factor for ischaemic stroke. Carotid revascularisation procedures are an effective method of primary and secondary stroke prevention. However, patients developed postoperative acute ischaemic lesions (AILs), which were identified via magnetic resonance imaging (MRI) of the brains. Most of the patients with these AILs lack clinically overt symptoms. AIMS: To assess the risk of ischaemic brain damage in patients with T2DM in the setting of carotid angioplasty with stenting (CAS) or carotid endarterectomy (CAE). MATERIALS AND METHODS: This open prospective study comprised of 164 patients with carotid atherosclerosis, who have undergone either CAS or CAE. Patients with T2DM were included in Group 1: 38 patients and 28 patients with CAE. Group 2 included patients without T2DM: 62 patients with CAS and 36 patients with CAE. All patients underwent a thorough neurological examination and diffusion-weighted brain MRI.
Ключевые слова:
Brain ischemia; Carotid angioplasty and stenting; Carotid endarterectomy; Diabetes mellitus type 2; Stroke
glucose; hemoglobin A1c; Article; brain damage; brain ischemia; carotid artery stenting; carotid atherosclerosis; carotid endarterectomy; cerebrovascular accident; comparative study; controlled study; diabetic patient; diffusion weighted imaging; fasting; glucose blood level; human; hyperglycemia; major clinical study; neurologic examination; non insulin dependent diabetes mellitus; nuclear magnetic resonance imaging; prospective study; revascularization; risk factor
Язык текста: Русский
ISSN: 2072-0378
Танашян М. М.
Антонова К. В.
Медведев Р. Б.
Скрyлев С. И.
Кротенкова М. В.
Романцова Т. И. Татьяна Ивановна 1959-
Tanashyan M. M.
Antonova K. V.
Medvedev R. B.
Skrylev S. I.
Krotenkova M. V.
Romantsova T. I. Tat`yana Ivanovna 1959-
Symptomatic and silent cerebral ischemia (detected on MRI) in patients with type 2 diabetes mellitus after carotid revascularization procedures [СИМПТОМНАЯ И АСИМПТОМНАЯ ИШЕМИЯ ГОЛОВНОГО МОЗГА (ПО ДАННЫМ МРТ) У БОЛЬНЫХ САХАРНЫМ ДИАБЕТОМ 2 ТИПА ПОСЛЕ КАРОТИДНОЙ РЕВАСКУЛЯРИЗАЦИИ]
Symptomatic and silent cerebral ischemia (detected on MRI) in patients with type 2 diabetes mellitus after carotid revascularization procedures...
Текст визуальный непосредственный
Сахарный диабет
Федеральное государственное бюджетное учреждение Национальный медицинский исследовательский центр эндокринологии Министерства здравоохранения Российск
Т. 22, Вып. 1 С. 14-24
2019
Статья
Brain ischemia Carotid angioplasty and stenting Carotid endarterectomy Diabetes mellitus type 2 Stroke
glucose hemoglobin A1c Article brain damage brain ischemia carotid artery stenting carotid atherosclerosis carotid endarterectomy cerebrovascular accident comparative study controlled study diabetic patient diffusion weighted imaging fasting glucose blood level human hyperglycemia major clinical study neurologic examination non insulin dependent diabetes mellitus nuclear magnetic resonance imaging prospective study revascularization risk factor
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a significant independent risk factor for ischaemic stroke. Carotid revascularisation procedures are an effective method of primary and secondary stroke prevention. However, patients developed postoperative acute ischaemic lesions (AILs), which were identified via magnetic resonance imaging (MRI) of the brains. Most of the patients with these AILs lack clinically overt symptoms. AIMS: To assess the risk of ischaemic brain damage in patients with T2DM in the setting of carotid angioplasty with stenting (CAS) or carotid endarterectomy (CAE). MATERIALS AND METHODS: This open prospective study comprised of 164 patients with carotid atherosclerosis, who have undergone either CAS or CAE. Patients with T2DM were included in Group 1: 38 patients and 28 patients with CAE. Group 2 included patients without T2DM: 62 patients with CAS and 36 patients with CAE. All patients underwent a thorough neurological examination and diffusion-weighted brain MRI.