Application of acyzol in the context of zinc deficiency and perspectives
Aliev G., Li Y., Chubarev V. N., Lebedeva S. A., Parshina L. N., Trofimov B. A., Sologova S. S., Makhmutova A., Avila-Rodriguez M. F., Klochkov S. G., Galenko-Yaroshevsky P. A., Tarasov V. V.
International Journal of Molecular Sciences
Vol.20, Issue9, Num.2104
Опубликовано: 2019
Тип ресурса: Статья
Аннотация:
Zinc is one of the most important essential trace elements. It is involved in more than 300 enzyme systems and is an indispensable participant in many biochemical processes. Zinc deficiency causes a number of disorders in the human body, the main ones being the delay of growth and puberty, immune disorders, and cognitive dysfunctions. There are over two billion people in the world suffering from zinc deficiency conditions. Acyzol, a zinc-containing medicine, developed as an antidote against carbon monoxide poisoning, demonstrates a wide range of pharmacological activities: Anti-inflammatory, reparative, detoxifying, immunomodulatory, bacteriostatic, hepatoprotective, adaptogenic, antioxidant, antihypoxic, and cardioprotective. The presence of zinc in the composition of Acyzol suggests the potential of the drug in the treatment and prevention of zinc deficiency conditions, such as Prasad’s disease, immune system pathology, alopecia, allergodermatoses, prostate dysfunction, psoriasis, st
Ключевые слова:
Acyzol; Carbon monoxide; Pharmacological activity; Zinc; Zinc deficiency conditions
acyzol; antidote; antioxidant; carbon monoxide; unclassified drug; imidazole derivative; N-vinylimidazole; trace element; zinc; zinc acetate; alcohol psychosis; alopecia; anodic stripping potentiometry; Article; atomic emission spectrometry; autoimmune disease; bacteriostatic activity; carbon monoxide intoxication; cataract; cell proliferation; cognitive defect; coronary artery disease; flame atomic absorption spectrometry; heart protection; mass spectrometry; Parkinson disease; periodontal disease; periodontitis; psoriasis; puberty; sickle cell anemia; stomatitis; zinc deficiency; animal; chemistry; clinical study; deficiency; human; mouse; nutritional disorder; preclinical study; treatment outcome; Animals; Clinical Studies as Topic; Drug Evaluation, Preclinical; Humans; Imidazoles; Mice; Nutrition Disorders; Trace Elements; Treatment Outcome; Zinc; Zinc Acetate
Язык текста: Английский
ISSN: 1661-6596
Aliev G. Gyumrakh 1958-
Li Y.
Chubarev V. N. Vladimir Nikolaevich 1954-
Lebedeva S. A. Svetlana Anatolyevna 1974-
Parshina L. N.
Trofimov B. A.
Sologova S. S. Susanna Sergeevna 1973-
Makhmutova A.
Avila-Rodriguez M. F.
Klochkov S. G.
Galenko-Yaroshevsky P. A.
Tarasov V. V. Vadim Vladimirovich 1987-
Алиев Г. Гюмрах 1958-
Ли Y.
Чубарев В. Н. Владимир Николаевич 1954-
Лебедева С. А. Светлана Анатольевна 1974-
Паршина Л. Н.
Трофимов Б. А.
Сологова С. С. Сусанна Сергеевна 1973-
Махмутова А.
Авила-Родригуез М. Ф.
Клочков С. Г.
Галенко-Ярошевскy П. А.
Тарасов В. В. Вадим Владимирович 1987-
Application of acyzol in the context of zinc deficiency and perspectives
Текст визуальный непосредственный
International Journal of Molecular Sciences
Vol.20, Issue9 Num.2104
2019
Статья
Acyzol Carbon monoxide Pharmacological activity Zinc Zinc deficiency conditions
acyzol antidote antioxidant carbon monoxide unclassified drug imidazole derivative N-vinylimidazole trace element zinc zinc acetate alcohol psychosis alopecia anodic stripping potentiometry Article atomic emission spectrometry autoimmune disease bacteriostatic activity carbon monoxide intoxication cataract cell proliferation cognitive defect coronary artery disease flame atomic absorption spectrometry heart protection mass spectrometry Parkinson disease periodontal disease periodontitis psoriasis puberty sickle cell anemia stomatitis zinc deficiency animal chemistry clinical study deficiency human mouse nutritional disorder preclinical study treatment outcome Animals Clinical Studies as Topic Drug Evaluation, Preclinical Humans Imidazoles Mice Nutrition Disorders Trace Elements Treatment Outcome Zinc Zinc Acetate
Zinc is one of the most important essential trace elements. It is involved in more than 300 enzyme systems and is an indispensable participant in many biochemical processes. Zinc deficiency causes a number of disorders in the human body, the main ones being the delay of growth and puberty, immune disorders, and cognitive dysfunctions. There are over two billion people in the world suffering from zinc deficiency conditions. Acyzol, a zinc-containing medicine, developed as an antidote against carbon monoxide poisoning, demonstrates a wide range of pharmacological activities: Anti-inflammatory, reparative, detoxifying, immunomodulatory, bacteriostatic, hepatoprotective, adaptogenic, antioxidant, antihypoxic, and cardioprotective. The presence of zinc in the composition of Acyzol suggests the potential of the drug in the treatment and prevention of zinc deficiency conditions, such as Prasad’s disease, immune system pathology, alopecia, allergodermatoses, prostate dysfunction, psoriasis, st