Аннотация:
Prostate cancer (PrC) is one of the most common tumors diagnosed in men. The detection rate of localized PrC has been dramatically enhanced by screening and the development of visualization methods. There are currently several techniques for focal treatment available, among which the most interesting in our opinion is high-intensity focused ultrasound (HIFU). Currently, HIFU hemiablation of PrC is not an established treatment, although evidence of its effectiveness and safety is growing. We have been performing HIFU hemiablation since 2013 and here report our results to add to the evidence on the effectiveness of the technique. Between October 2013 and December 2016, we performed HIFU hemiablation of the prostate for a total of 35 patients with confirmed PrC stage <cT2a at our urology clinic and retrospectively examined duration of ablation, pre- and postoperative prostate-specific antigen (PSA) levels, prostate volume, erectile function, and dysuria. The mean duration of ablation was
Ключевые слова:
Focal therapy; HIFU ablation; Prostate cancer; Ultrasound hemiablation
prostate specific antigen; prostate specific antigen; ablation therapy; adult; aged; Article; cancer staging; case study; clinical article; clinical effectiveness; controlled study; dysuria; erectile dysfunction; follow up; high intensity focused ultrasound; histopathology; human; International Prostate Symptom Score; length of stay; male; medical device complication; micturition; minimal residual disease; minimally invasive surgery; mucosa inflammation; nuclear magnetic resonance imaging; operation duration; patient safety; postoperative complication; postoperative period; preoperative evaluation; priority journal; prostate biopsy; prostate cancer; prostate volume; protein blood level; recurrence risk; reliability; retrospective study; blood; diagnostic imaging; middle aged; pathology; procedures; prostate; prostate tumor; radiation response; salvage therapy; shock wave therapy; tumor recurrence; Aged; Extracorporeal Shockwave Therapy; Humans; Magnetic Resonance Imaging; Male; Middle
Gly'bochko P. V. Petr Vitalyevich 1964-
Amosov A. V. Aleksandr Valentinovich 1953-
Krupinov G. E. German Evgenyevich 1970-
Petrovskii N. V.
Lumpov I. S.
Глыбочко П. В. Петр Витальевич 1964-
Амосов А. В. Александр Валентинович 1953-
Крупинов Г. Е. Герман Евгеньевич 1970-
Петровскии Н. В.
Лумпов И. С.
Hemiablation of Localized Prostate Cancer by High-Intensity Focused Ultrasound: A Series of 35 Cases
Текст визуальный непосредственный
Oncology
S. Karger AG
Vol.97, Issue1 P. 44-48
2019
Статья
Focal therapy HIFU ablation Prostate cancer Ultrasound hemiablation
prostate specific antigen prostate specific antigen ablation therapy adult aged Article cancer staging case study clinical article clinical effectiveness controlled study dysuria erectile dysfunction follow up high intensity focused ultrasound histopathology human International Prostate Symptom Score length of stay male medical device complication micturition minimal residual disease minimally invasive surgery mucosa inflammation nuclear magnetic resonance imaging operation duration patient safety postoperative complication postoperative period preoperative evaluation priority journal prostate biopsy prostate cancer prostate volume protein blood level recurrence risk reliability retrospective study blood diagnostic imaging middle aged pathology procedures prostate prostate tumor radiation response salvage therapy shock wave therapy tumor recurrence Aged Extracorporeal Shockwave Therapy Humans Magnetic Resonance Imaging Male Middle
Prostate cancer (PrC) is one of the most common tumors diagnosed in men. The detection rate of localized PrC has been dramatically enhanced by screening and the development of visualization methods. There are currently several techniques for focal treatment available, among which the most interesting in our opinion is high-intensity focused ultrasound (HIFU). Currently, HIFU hemiablation of PrC is not an established treatment, although evidence of its effectiveness and safety is growing. We have been performing HIFU hemiablation since 2013 and here report our results to add to the evidence on the effectiveness of the technique. Between October 2013 and December 2016, we performed HIFU hemiablation of the prostate for a total of 35 patients with confirmed PrC stage <cT2a at our urology clinic and retrospectively examined duration of ablation, pre- and postoperative prostate-specific antigen (PSA) levels, prostate volume, erectile function, and dysuria. The mean duration of ablation was