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Mucosal immunity of the digestive and respiratory tracts: Possibilities of preventing and treatment of infectious diseases

Kanner E. V., Pechkurov D. V., Gorelov A. V.
Инфекционные болезни
Vol.17, Issue1, P. 93-99
Опубликовано: 2019
Тип ресурса: Статья

DOI:10.20953/1729-9225-2019-1-93-99

Аннотация:
The immune system of the body’s mucous membranes plays an enormous role in the development, maintenance and regulation of immune homeostasis, being a significant element of the multicomponent immunity system. The structural basis of local immunity is formed by mucosa-associated lymphoid tissue (MALT). At present, a bulk of research data has been accumulated indicating that segments of mucous membranes of the body’s various systems closely interact with each other, in conformity with comprehensive regulatory influences. Especially close is this interaction between the digestive and respiratory tracts, research works have shown that vaccination of the mucosa of one segment enhances the defence function of the mucosa of another segment, and virus infection results in the appearance of virus-specific concentrations of immunoglobulins in mucosal secretion of another segment. Influence on intestinal microbiota might be a convenient tool for prevention of not only gastrointestinal but also re
Ключевые слова:
Antimicrobial peptides; Common mucosal immune system theory; Digestive system; Microbiota; Mucosal immunity; Probiotics; Respiratory tract
immunoglobulin; Article; digestive system; immunity; mucosa; mucosal immunity; respiratory system; vaccination; virus infection
Язык текста: Английский
ISSN: 2414-9691
Kanner E. V.
Pechkurov D. V.
Gorelov A. V. Aleksandr Vasilyevich 1958-
Каннер Е. В.
Печкуров Д. В.
Горелов А. В. Александр Васильевич 1958-
Mucosal immunity of the digestive and respiratory tracts: Possibilities of preventing and treatment of infectious diseases
Текст визуальный непосредственный
Инфекционные болезни
ООО "Издательство "Династия"
Vol.17, Issue1 P. 93-99
2019
Статья
Antimicrobial peptides Common mucosal immune system theory Digestive system Microbiota Mucosal immunity Probiotics Respiratory tract
immunoglobulin Article digestive system immunity mucosa mucosal immunity respiratory system vaccination virus infection
The immune system of the body’s mucous membranes plays an enormous role in the development, maintenance and regulation of immune homeostasis, being a significant element of the multicomponent immunity system. The structural basis of local immunity is formed by mucosa-associated lymphoid tissue (MALT). At present, a bulk of research data has been accumulated indicating that segments of mucous membranes of the body’s various systems closely interact with each other, in conformity with comprehensive regulatory influences. Especially close is this interaction between the digestive and respiratory tracts, research works have shown that vaccination of the mucosa of one segment enhances the defence function of the mucosa of another segment, and virus infection results in the appearance of virus-specific concentrations of immunoglobulins in mucosal secretion of another segment. Influence on intestinal microbiota might be a convenient tool for prevention of not only gastrointestinal but also re