Toxic epidermal necrolysis as a variant of severe skin lesions in systemic lupus erythematosus
Воробьева Л. Д., Асеева Е. А., Соловьев С. К., Белоусова Т. А., Лопатина Н. Е., Сажина Е. Г., Серикова Г. В.
Научно-практическая ревматология
Т. 56, Вып. 6, С. 785-790
Опубликовано: 2018
Тип ресурса: Статья
DOI:10.14412/1995-4484-2018-785-790
Аннотация:
Toxic epidermal necrolysis (TEN) has been long believed to be the most severe manifestation of drug allergy. However, cutaneous changes as TEN in systemic lupus erythematosus (SLE) were first described in the late 1970s. As of now, the English-language literature published reports of 30 cases of such lesions in SLE. This paper describes a clinical case of TEN as a direct manifestation of SLE; the positive experience has been first depicted in using not only intravenous immunoglobulin, but also rituximab with a good therapeutic effect in Russian clinical practice. © 2018 Ima-Press Publishing House. All rights reserved.
Ключевые слова:
Clinical case; Intravenous immunoglobulin; Rituximab; Systemic lupus erythematosus; Toxic epidermal necrolysis
Язык текста: Русский
ISSN: 1995-4492
Воробьева Л. Д.
Асеева Е. А.
Соловьев С. К.
Белоусова Т. А. Татьяна Алексеевна 1947-
Лопатина Н. Е.
Сажина Е. Г.
Серикова Г. В.
Vorobyeva L. D.
Aseeva E. A.
Solovyev S. K.
Belousova T. A. Tat`yana Alekseevna 1947-
Lopatina N. E.
Sazhina E. G.
Serikova G. V.
Toxic epidermal necrolysis as a variant of severe skin lesions in systemic lupus erythematosus
Текст визуальный непосредственный
Научно-практическая ревматология
ИМА-Пресс
Т. 56, Вып. 6 С. 785-790
2018
Статья
Clinical case Intravenous immunoglobulin Rituximab Systemic lupus erythematosus Toxic epidermal necrolysis
Toxic epidermal necrolysis (TEN) has been long believed to be the most severe manifestation of drug allergy. However, cutaneous changes as TEN in systemic lupus erythematosus (SLE) were first described in the late 1970s. As of now, the English-language literature published reports of 30 cases of such lesions in SLE. This paper describes a clinical case of TEN as a direct manifestation of SLE; the positive experience has been first depicted in using not only intravenous immunoglobulin, but also rituximab with a good therapeutic effect in Russian clinical practice. © 2018 Ima-Press Publishing House. All rights reserved.