Liver transplantation from sexagenarian and older
Готье С. В., Корнилов М. Н., Милосердов И. А., Минина М. Г., Круглов Д. Н., Зубенко С. И.
Вестник трансплантологии и искусственных органов
Т. 20, Вып. 1, С. 6-12
Опубликовано: 2018
Тип ресурса: Статья
DOI:10.15825/1995-1191-2018-1-6-12
Аннотация:
Donor organs shortage leads to extending criteria for deceased liver donation in the whole world. Aim: To compare results of deceased donor liver transplantation (DDLT) depending of donor age over 60 years old. Materials and methods: The study includes 390 DDLT from January 2010 to November 2017. All liver donors separated by age for two groups: I - 60 years and older (n = 26); II - younger than 60 years (n = 364). All donors were standardized by demographic, laboratory fi ndings and inotropic drug requirement. Results: no difference between both groups in severity of ischemia-reperfusion injury, ICU or in-hospital staying (median 2 and 7,5 days respectively) was found. There is also no difference between biliary or vascular complication rate. 5-year actuarial survival rate found no difference between both groups (I: 70[%]: II: 76[%], p = 0,54). Conclusion. Using grafts from donors older than 60 years don't worsen early and late results of DDLT. Care should be taken to avoid other risk fac
Ключевые слова:
Deceased donor liver transplantation; Elderly deceased donors; Expanded criteria donor
Язык текста: Русский
ISSN: 2412-6160
Готье С. В. Сергей Владимирович 1947-
Корнилов М. Н.
Милосердов И. А. Игорь Александрович 1975-
Минина М. Г.
Круглов Д. Н.
Зубенко С. И.
Gotye S. V. Sergej Vladimirovich 1947-
Kornilov M. N.
Miloserdov I. A. Igor` Aleksandrovich 1975-
Minina M. G.
Kruglov D. N.
Zubenko S. I.
Liver transplantation from sexagenarian and older
Текст визуальный непосредственный
Вестник трансплантологии и искусственных органов
Федеральный научный центр трансплантологии и искусственных органов им. академика В.И. Шумакова
Т. 20, Вып. 1 С. 6-12
2018
Статья
Deceased donor liver transplantation Elderly deceased donors Expanded criteria donor
Donor organs shortage leads to extending criteria for deceased liver donation in the whole world. Aim: To compare results of deceased donor liver transplantation (DDLT) depending of donor age over 60 years old. Materials and methods: The study includes 390 DDLT from January 2010 to November 2017. All liver donors separated by age for two groups: I - 60 years and older (n = 26); II - younger than 60 years (n = 364). All donors were standardized by demographic, laboratory fi ndings and inotropic drug requirement. Results: no difference between both groups in severity of ischemia-reperfusion injury, ICU or in-hospital staying (median 2 and 7,5 days respectively) was found. There is also no difference between biliary or vascular complication rate. 5-year actuarial survival rate found no difference between both groups (I: 70[%]: II: 76[%], p = 0,54). Conclusion. Using grafts from donors older than 60 years don't worsen early and late results of DDLT. Care should be taken to avoid other risk fac