Predictors of poor outcomes in acute exacerbations of chronic obstructive pulmonary disease
Сое А. К., Авдеев С. Н., Нуралиева Г. С., Гайнитдинова В. В., Чучалин А. Г.
Пульмонология
Т. 28, Вып. 4, С. 446-452
Опубликовано: 2018
Тип ресурса: Статья
DOI:10.18093/0869-0189-2018-28-4-446-452
Аннотация:
The aim of this study was to identify predictors of poor outcomes in patients hospitalized for severe acute exacerbation of COPD (AECOPD). Methods. This retrospective, observational cohort study was conducted in Pulmonology Department of a city hospital in 2015 - 2016 and involved patients hospitalized for severe AECOPD. Patients were divided according to outcomes. Poor outcomes included at least one of the followings: the need in invasive (IMV) or non-invasive (NIV) ventilation, admission to ICU, in-hospital death and COPD-related readmission during 2 months. Demographic, clinical, laboratory parameters, pulmonary function tests and blood gas analysis were analyzed; different multidimensional prognostic scores were also evaluated and compared. Results. Of 121 patients included, a poor outcome had occurred in 45 patients (37[%]). Among them, NIV was required in 21 (17[%]), IMV in 8 (6[%]), and admission to ICU in 16 patients (13[%]); death was registered in 6 patients (5[%]) and readmission in 2
Ключевые слова:
COPD; Outcomes; Predictors; Prognostic factors; Severe exacerbations
ambulance; APACHE; Article; blood gas analysis; chronic obstructive lung disease; clinical outcome; cohort analysis; disease exacerbation; hospital admission; hospital readmission; hospitalization; human; hypercapnia; hypoxemia; length of stay; lung function test; major clinical study; noninvasive ventilation; observational study; oxygen therapy; retrospective study
Язык текста: Русский
ISSN: 0869-0189
Сое А. К.
Авдеев С. Н. Сергей Николаевич 1968-
Нуралиева Г. С.
Гайнитдинова В. В. Вилия Вилевна 1975-
Чучалин А. Г.
Soe A. K.
Avdeev S. N. Sergej Nikolaevich 1968-
Nuralieva G. S.
Gaynitdinova V. V. Viliya Vilevna 1975-
Chuchalin A. G.
Predictors of poor outcomes in acute exacerbations of chronic obstructive pulmonary disease
Текст визуальный непосредственный
Пульмонология
Научно-практический журнал "Пульмонология"
Т. 28, Вып. 4 С. 446-452
2018
Статья
COPD Outcomes Predictors Prognostic factors Severe exacerbations
ambulance APACHE Article blood gas analysis chronic obstructive lung disease clinical outcome cohort analysis disease exacerbation hospital admission hospital readmission hospitalization human hypercapnia hypoxemia length of stay lung function test major clinical study noninvasive ventilation observational study oxygen therapy retrospective study
The aim of this study was to identify predictors of poor outcomes in patients hospitalized for severe acute exacerbation of COPD (AECOPD). Methods. This retrospective, observational cohort study was conducted in Pulmonology Department of a city hospital in 2015 - 2016 and involved patients hospitalized for severe AECOPD. Patients were divided according to outcomes. Poor outcomes included at least one of the followings: the need in invasive (IMV) or non-invasive (NIV) ventilation, admission to ICU, in-hospital death and COPD-related readmission during 2 months. Demographic, clinical, laboratory parameters, pulmonary function tests and blood gas analysis were analyzed; different multidimensional prognostic scores were also evaluated and compared. Results. Of 121 patients included, a poor outcome had occurred in 45 patients (37[%]). Among them, NIV was required in 21 (17[%]), IMV in 8 (6[%]), and admission to ICU in 16 patients (13[%]); death was registered in 6 patients (5[%]) and readmission in 2