Clinical efficacy of vaccination against hemophilic type B and pneumococcal infections in children with chronic respiratory diseases
Магаршак О. О., Костинов М. П., Краковскайа А. В., Козлов В. К., Благовидов Д. А., Полишчук В. Б., Рyжов А. А., Костинов А. М.
Педиатрия. Журнал им. Г.Н. Сперанского
Т. 97, Вып. 2, С. 122-129
Опубликовано: 2018
Тип ресурса: Статья
DOI:10.24110/0031-403X-2018-97-2-122-129
Аннотация:
Materials and methods: the study assessed safety and clinical efficacy of combined use of vaccine preparations against S. pneumoniae and H. influenzae type b, leading pathogens in bronchopulmonary diseases exacerbations development, in previously unvaccinated 38 children aged 2–17 years with chronic bronchopulmonary diseases: 19 with malformations of the bronchi and lungs (MBL); 10 with malformations of bronchi and lungs in combination with bronchial asthma (MBL+BA); 9 with bronchial asthma (BA). The control group consisted of 19 unvaccinated children of the same age with a similar pathology. Combined vaccination against these infections, as well as their separate administration, did not cause adverse effects. Results: a year after the introduction of Pneumo-23 vaccine, the incidence of acute respiratory infections (ARI) and exacerbations of the main disease decreased by 2,3 times; Act-HIB by 2,3 and 2,1 times respectively; by 1,7 and 1,5 times respectively with simultaneous administra
Ключевые слова:
Bronchial asthma; Children; Haemophilus influenza; Lungs malformations; Pneumococcus; Vaccine prophylaxis
Язык текста: Русский
ISSN: 1990-2182
Магаршак О. О.
Костинов М. П. Михаил Петрович 1956-
Краковскайа А. В.
Козлов В. К.
Благовидов Д. А.
Полишчук В. Б.
Рyжов А. А.
Костинов А. М.
Magarshak O. O.
Kostinov M. P. Mikhail Petrovich 1956-
Krakovskaya A. V.
Kozlov V. K.
Blagovidov D. A.
Polishchuk V. B.
Ryzhov A. A.
Kostinov A. M.
Clinical efficacy of vaccination against hemophilic type B and pneumococcal infections in children with chronic respiratory diseases
Текст визуальный непосредственный
Педиатрия. Журнал им. Г.Н. Сперанского
ООО "Педиатрия"
Т. 97, Вып. 2 С. 122-129
2018
Статья
Bronchial asthma Children Haemophilus influenza Lungs malformations Pneumococcus Vaccine prophylaxis
Materials and methods: the study assessed safety and clinical efficacy of combined use of vaccine preparations against S. pneumoniae and H. influenzae type b, leading pathogens in bronchopulmonary diseases exacerbations development, in previously unvaccinated 38 children aged 2–17 years with chronic bronchopulmonary diseases: 19 with malformations of the bronchi and lungs (MBL); 10 with malformations of bronchi and lungs in combination with bronchial asthma (MBL+BA); 9 with bronchial asthma (BA). The control group consisted of 19 unvaccinated children of the same age with a similar pathology. Combined vaccination against these infections, as well as their separate administration, did not cause adverse effects. Results: a year after the introduction of Pneumo-23 vaccine, the incidence of acute respiratory infections (ARI) and exacerbations of the main disease decreased by 2,3 times; Act-HIB by 2,3 and 2,1 times respectively; by 1,7 and 1,5 times respectively with simultaneous administra