Clinical and immunological efficacy of conjugated pneumococcal vaccine in children with compensated chronic tonsillitis
Абабиy И. И., Данилов Л. А., Гинда С. С., Манюк М. К., Абабиy П. И., Костинов М. П.
Педиатрия. Журнал им. Г.Н. Сперанского
Т. 97, Вып. 2, С. 134-139
Опубликовано: 2018
Тип ресурса: Статья
DOI:10.24110/0031-403X-2018-97-2-134-139
Аннотация:
The article presents results of conjugated pneumococcal vaccine use in combination with basic therapy in 64 children with chronic compensated tonsillitis. The study showed that vaccination assists activation of T-lymphocytes subpopulation, increases sensitization to bacterial antigens, normalization of proinflammatory cytokines content, which is clinically manifested in a significant decrease in acute respiratory infections incidences and antibacterial therapy courses for 2 years after vaccination compared to patients receiving a traditional therapy course. © 2018, Pediatria Ltd. All rights reserved.
Ключевые слова:
Cellular immunity; Children; Chronic tonsillitis; Conjugated pneumococcal vaccine; Markers of inflammation
Язык текста: Русский
ISSN: 1990-2182
Абабиy И. И.
Данилов Л. А.
Гинда С. С.
Манюк М. К.
Абабиy П. И.
Костинов М. П. Михаил Петрович 1956-
Ababiy I. I.
Danilov L. A.
Ginda S. S.
Manyuk M. K.
Ababiy P. I.
Kostinov M. P. Mikhail Petrovich 1956-
Clinical and immunological efficacy of conjugated pneumococcal vaccine in children with compensated chronic tonsillitis
Текст визуальный непосредственный
Педиатрия. Журнал им. Г.Н. Сперанского
ООО "Педиатрия"
Т. 97, Вып. 2 С. 134-139
2018
Статья
Cellular immunity Children Chronic tonsillitis Conjugated pneumococcal vaccine Markers of inflammation
The article presents results of conjugated pneumococcal vaccine use in combination with basic therapy in 64 children with chronic compensated tonsillitis. The study showed that vaccination assists activation of T-lymphocytes subpopulation, increases sensitization to bacterial antigens, normalization of proinflammatory cytokines content, which is clinically manifested in a significant decrease in acute respiratory infections incidences and antibacterial therapy courses for 2 years after vaccination compared to patients receiving a traditional therapy course. © 2018, Pediatria Ltd. All rights reserved.