Аннотация:
The term complex sleep apnea syndrome (Comp-SAS) refers to a specific variant of respiratory impairment during sleep characterized by the appearance or significant increases in the number of episodes of central apnea and hypopnea after starting CPAP therapy for obstructive sleep apnea syndrome (OSAS). The mechanisms producing Comp-SAS are not fully understood. It is possible that respiration with positive pressure and elimination of pharyngeal obstruction in some patients lead to increases in pulmonary ventilation and decreases in P a CO 2 to below the individual threshold required for stimulating respiration. The prevalence of Comp-SAS is 5–20[%] of patients with OSAS receiving CPAP therapy. Significant clinical predictors for Comp-SAS have not been established, though this respiratory disorder is known to occur more frequently in male patients, older patients, those with severe OSAS, and those with cardiovascular diseases such as ischemic heart diseases, atrial fibrillation, or chronic
Ключевые слова:
adaptive servo ventilation; central sleep apnea; CPAP; obstructive sleep apnea; sleep apnea
arterial carbon dioxide tension; Article; breathing rate; cardiovascular risk; Cheyne Stokes breathing; clinical feature; disease severity; human; lung ventilation; pathogenesis; positive end expiratory pressure; prevalence; sleep disordered breathing; treatment duration
Pal’man A. D.
Пал’ман А. Д.
Complex Sleep Apnea
Текст визуальный непосредственный
Neuroscience and Behavioral Physiology
Springer New York Consultants Bureau
Vol.49, Issue1 P. 48-53
2019
Статья
adaptive servo ventilation central sleep apnea CPAP obstructive sleep apnea sleep apnea
arterial carbon dioxide tension Article breathing rate cardiovascular risk Cheyne Stokes breathing clinical feature disease severity human lung ventilation pathogenesis positive end expiratory pressure prevalence sleep disordered breathing treatment duration
The term complex sleep apnea syndrome (Comp-SAS) refers to a specific variant of respiratory impairment during sleep characterized by the appearance or significant increases in the number of episodes of central apnea and hypopnea after starting CPAP therapy for obstructive sleep apnea syndrome (OSAS). The mechanisms producing Comp-SAS are not fully understood. It is possible that respiration with positive pressure and elimination of pharyngeal obstruction in some patients lead to increases in pulmonary ventilation and decreases in P a CO 2 to below the individual threshold required for stimulating respiration. The prevalence of Comp-SAS is 5–20[%] of patients with OSAS receiving CPAP therapy. Significant clinical predictors for Comp-SAS have not been established, though this respiratory disorder is known to occur more frequently in male patients, older patients, those with severe OSAS, and those with cardiovascular diseases such as ischemic heart diseases, atrial fibrillation, or chronic