Аннотация:
In a study of 537 patients with chronic generalized periodontitis and metabolic syndrome (MS) depending on age and gender, it was found that the increase of TNF-α and IL-6 in the content of periodontal pockets correlated with the severity of chronic generalized periodontitis and MS. For these cytokines, there was a clear gender relationship: women had higher levels in periodontal pocket content than men. For IL-1β and IL-4 cytokines, there is no coupling between the severity of the damage and the level of cytokines in the periodontal pocket. The developed model for calculating the risk of chronic generalized periodontitis depending on the level of TNF-α in the patient's periodontal pockets allows predicting and monitoring the dynamics of the disease.При обследовании 537 пациентов с хроническим генерализованным пародонтитом и метаболическим синдромом (МС) в зависимости от пола и возраста установлено, что уровень повышения в содержимом пародонтальных карманов (ПК) ФНО-α и ИЛ-6 коррелиров
Ключевые слова:
chronic generalized periodontitis; cytokines; gender; metabolic syndrome; TNF; tumor necrosis factor
cytokine; tumor necrosis factor; chronic periodontitis; complication; female; human; male; metabolic syndrome X; metabolism; periodontal pocket; Chronic Periodontitis; Cytokines; Female; Humans; Male; Metabolic Syndrome; Periodontal Pocket; Tumor Necrosis Factor-alpha
Петрухина Н. Б. Наталия Борисовна 1977-
Зорина О. А. Оксана Александровна 1968-
Ших Е. В. Евгения Валерьевна 1962-
Картышева Е. В. Екатерина Владимировна 1990-
Кудрявцев А. В. Александр Владимирович 1992-
Беркутова И. С.
Petrukhina N. B. Nataliya Borisovna 1977-
Zorina O. A. Oksana Aleksandrovna 1968-
Shikh E. V. Evgeniya Valeryevna 1962-
Karty'sheva E. V. Ekaterina Vladimirovna 1990-
Kudryavtsev A. V. Aleksandr Vladimirovich 1992-
Berkutova I. S.
Changes in proinflammatory cytokines in patients with chronic periodontitis and metabolic syndrome, depending on gender and age [Izmenenie provospalitel'nykh tsitokinov u patsientov s khronicheskim parodontitom na fone metabolicheskogo sindroma v zavisimosti ot pola i vozrasta]
Changes in proinflammatory cytokines in patients with chronic periodontitis and metabolic syndrome, depending on gender and age [Izmenenie...
Текст визуальный непосредственный
Стоматология
Издательство Медиа Сфера
Т. 97, Вып. 6 С. 38-44
2018
Статья
chronic generalized periodontitis cytokines gender metabolic syndrome TNF tumor necrosis factor
cytokine tumor necrosis factor chronic periodontitis complication female human male metabolic syndrome X metabolism periodontal pocket Chronic Periodontitis Cytokines Female Humans Male Metabolic Syndrome Periodontal Pocket Tumor Necrosis Factor-alpha
In a study of 537 patients with chronic generalized periodontitis and metabolic syndrome (MS) depending on age and gender, it was found that the increase of TNF-α and IL-6 in the content of periodontal pockets correlated with the severity of chronic generalized periodontitis and MS. For these cytokines, there was a clear gender relationship: women had higher levels in periodontal pocket content than men. For IL-1β and IL-4 cytokines, there is no coupling between the severity of the damage and the level of cytokines in the periodontal pocket. The developed model for calculating the risk of chronic generalized periodontitis depending on the level of TNF-α in the patient's periodontal pockets allows predicting and monitoring the dynamics of the disease.При обследовании 537 пациентов с хроническим генерализованным пародонтитом и метаболическим синдромом (МС) в зависимости от пола и возраста установлено, что уровень повышения в содержимом пародонтальных карманов (ПК) ФНО-α и ИЛ-6 коррелиров