Laser video fluorescence diagnosis of stomach diseases
Loshchenov M. V., Levkin V. V., Chernousov A. F., Kalyagina N. A., Kharnas S. S., Zavodnov V. Y., Линков К. Г., Musayev G. H., Egorov A. V., Karpova R. V., Рyбин В. К., Khorobry'kh T. V.
Современные технологии в медицине
Vol.10, Issue4, P. 42-48
Опубликовано: 2018
Тип ресурса: Статья
DOI:10.17691/stm2018.10.4.05
Аннотация:
The aim of the study was to assess the efficiency of the method for registration of video fluorescence of 5-ALA-induced protoporphyrin IX in stomach and esophagus diseases, to adapt it for clinical conditions, i.e. for conducting differential diagnosis and detecting precancer conditions, and to formulate recommendations on the best photosensitizer doses and time of application in order to make the diagnostic procedure for these diseases more accurate. Materials and Methods. Registration of fluorescence for diagnostic purposes was performed on 57 patients with gastropathology (mainly with stomach cancer) with the help of single-channel (n=50) and dual-channel (n=7) laser video fluorescence registration systems. The study was performed using 5-aminolevulinic acid (5-ALA) (Alasens). 39 endoscopic, 18 intraoperative/laparoscopic investigations, and 7 studies on the macropreparation have been performed. Results. When both systems were used, no fluorescence was registered in cases of stomach
Ключевые слова:
5-aminolevulinic acid; Alasens; Gastric cancer; Laser diagnosis; Laser video fluorescence diagnosis; Video fluorescence
aminolevulinic acid; photosensitizing agent; Article; atrophic gastritis; Barrett esophagus; chronic gastritis; diagnostic accuracy; differential diagnosis; dysplasia; fluorescence; gastrectomy; human; laparoscopy; laser video fluorescence; major clinical study; precancer; spectroscopy; stomach disease; stomach ulcer; tumor necrosis
Язык текста: Английский
ISSN: 2076-4243
Loshchenov M. V.
Levkin V. V. Vladimir Veniaminovich 1965-
Chernousov A. F. Aleksandr Fedorovich 1938-
Kalyagina N. A.
Kharnas S. S. Sergej Saulovich 1955-
Zavodnov V. Y.
Линков К. Г.
Musayev G. H.
Egorov A. V.
Karpova R. V. Radmila Vladimirovna 1971-
Рyбин В. К.
Khorobry'kh T. V. Tat`yana Vitalyevna 1968-
Лошченов М. В.
Левкин В. В. Владимир Вениаминович 1965-
Черноусов А. Ф. Александр Федорович 1938-
Калягина Н. А.
Харнас С. С. Сергей Саулович 1955-
Заводнов В. Y.
Linkov K. G.
Мусайев Г. Х.
Егоров А. В.
Карпова Р. В. Радмила Владимировна 1971-
Rybin V. K.
Хоробрых Т. В. Татьяна Витальевна 1968-
Laser video fluorescence diagnosis of stomach diseases
Текст визуальный непосредственный
Современные технологии в медицине
Нижегородская государственная медицинская академия
Vol.10, Issue4 P. 42-48
2018
Статья
5-aminolevulinic acid Alasens Gastric cancer Laser diagnosis Laser video fluorescence diagnosis Video fluorescence
aminolevulinic acid photosensitizing agent Article atrophic gastritis Barrett esophagus chronic gastritis diagnostic accuracy differential diagnosis dysplasia fluorescence gastrectomy human laparoscopy laser video fluorescence major clinical study precancer spectroscopy stomach disease stomach ulcer tumor necrosis
The aim of the study was to assess the efficiency of the method for registration of video fluorescence of 5-ALA-induced protoporphyrin IX in stomach and esophagus diseases, to adapt it for clinical conditions, i.e. for conducting differential diagnosis and detecting precancer conditions, and to formulate recommendations on the best photosensitizer doses and time of application in order to make the diagnostic procedure for these diseases more accurate. Materials and Methods. Registration of fluorescence for diagnostic purposes was performed on 57 patients with gastropathology (mainly with stomach cancer) with the help of single-channel (n=50) and dual-channel (n=7) laser video fluorescence registration systems. The study was performed using 5-aminolevulinic acid (5-ALA) (Alasens). 39 endoscopic, 18 intraoperative/laparoscopic investigations, and 7 studies on the macropreparation have been performed. Results. When both systems were used, no fluorescence was registered in cases of stomach