Аннотация:
RELEVANCE: Erectile dysfunction (ED) is a common condition. Pharmacological management of ED involves medications produced by chemical synthesis. Despite high efficiency, their use is often accompanied by some side effects. Considering this, herbal preparations with sufficient efficacy and greater safety have received much attention.AIM: To compare the efficacy and safety of two herbal preparations (EFFEX Tribulus and Tribestan) based on Tribulus Terrestris herb dry extract in patients with ED.MATERIALS AND METHODS: A total of 173 patients were enrolled in the study, of whom 87 (group I) and 86 (group II) received EFFEX Tribulus and Tribestan, respectively. The mean age of patients was 42.2+/-11.5 years in group I and 42.8+/-11.2 years in group II. One hundred fifty two patients completed the study. The follow-up was 13 weeks (the herbal preparation dose was titrated at week five after the treatment initiation). The effectiveness of treatment was assessed on five follow-up visits using
Ключевые слова:
EFFEX Tribulus; erectile dysfunction; extract of Tribulus terrestris; Tribestan
plant extract; plant medicinal product; saponin; tribestan; adult; chemistry; clinical trial; comparative study; controlled study; erectile dysfunction; human; male; middle aged; multicenter study; pathophysiology; phytotherapy; randomized controlled trial; Tribulus; Adult; Erectile Dysfunction; Humans; Male; Middle Aged; Phytotherapy; Plant Extracts; Plant Preparations; Saponins; Tribulus
Спивак Л. Г. Леонид Григорьевич 1974-
Платонова Д. В.
Еникеев Д. В. Дмитрий Викторович 1982-
Рапопорт Л. М. Леонид Моисеевич 1956-
Винаров А. З. Андрей Зиновьевич 1956-
Демидко Ю. Л. Юрий Леонидович 1968-
Spivak L. G. Leonid Grigoryevich 1974-
Platonova D. V.
Enikeev D. V. Dmitrij Viktorovich 1982-
Rapoport L. M. Leonid Moiseevich 1956-
Vinarov A. Z. Andrej Zinovyevich 1956-
Demidko Yu. L. Yurij Leonidovich 1968-
Results of a comparative multi-center randomized clinical study of efficacy and safety of EFFEX Tribulus and Tribestan in patients with erectile dysfunction
Results of a comparative multi-center randomized clinical study of efficacy and safety of EFFEX Tribulus and Tribestan in patients with erectile...
Текст визуальный непосредственный
Урология
Бионика Медиа
Вып. 2 С. 54-61
2018
Статья
EFFEX Tribulus erectile dysfunction extract of Tribulus terrestris Tribestan
plant extract plant medicinal product saponin tribestan adult chemistry clinical trial comparative study controlled study erectile dysfunction human male middle aged multicenter study pathophysiology phytotherapy randomized controlled trial Tribulus Adult Erectile Dysfunction Humans Male Middle Aged Phytotherapy Plant Extracts Plant Preparations Saponins Tribulus
RELEVANCE: Erectile dysfunction (ED) is a common condition. Pharmacological management of ED involves medications produced by chemical synthesis. Despite high efficiency, their use is often accompanied by some side effects. Considering this, herbal preparations with sufficient efficacy and greater safety have received much attention.AIM: To compare the efficacy and safety of two herbal preparations (EFFEX Tribulus and Tribestan) based on Tribulus Terrestris herb dry extract in patients with ED.MATERIALS AND METHODS: A total of 173 patients were enrolled in the study, of whom 87 (group I) and 86 (group II) received EFFEX Tribulus and Tribestan, respectively. The mean age of patients was 42.2+/-11.5 years in group I and 42.8+/-11.2 years in group II. One hundred fifty two patients completed the study. The follow-up was 13 weeks (the herbal preparation dose was titrated at week five after the treatment initiation). The effectiveness of treatment was assessed on five follow-up visits using