Аннотация:
Vitamin D deficiency is widespread worldwide and present in about 30-50[%] of population. In most cases, this problem is associated with musculoskeletal system pathology: Rickets in children, and osteomalacia or osteoporosis in adults. However, in recent years, convincing data was obtained on the links between Vitamin D deficiency and cardiovascular pathology. Low Vitamin D levels in humans are associated with the unfavorable cardiovascular risk factors, such as arterial hypertension (AH), diabetes mellitus, and dyslipidemia, which are the predictors of the severe cardiovascular diseases, including strokes and infarctions. It has been demonstrated that Vitamin D has a strong vasoptotective effect via endothelial dysfunction improvement, prevents blood vessels and myocardium remodeling, improves blood pressure parameters, reduces the risk of development of left ventricular hypertrophy, slows down fibrosis, reduces the risk of atherosclerosis, reduces insulin resistance, and also affects i
Ключевые слова:
1,25(OH)2D; 25(OH)D; arterial hypertension; atherosclerosis; cardiology; chronic heart failure; heart rhythm disorder; Vitamin D Deficiency
protective agent; vitamin D; cardiovascular disease; heart ventricle remodeling; human; metabolism; pathophysiology; physiology; risk factor; vascular endothelium; vitamin D deficiency; Cardiovascular Diseases; Endothelium, Vascular; Humans; Protective Agents; Risk Factors; Ventricular Remodeling; Vitamin D; Vitamin D Deficiency
Подзолков В. И. Валерий Иванович 1948-
Покровская А. Е. Анна Евгеньевна 1976-
Панасенко О. И. Оксана Игоревна 1995-
Podzolkov V. I. Valerij Ivanovich 1948-
Pokrovskaya A. E. Anna Evgenyevna 1976-
Panasenko O. I. Oksana Igorevna 1995-
Vitamin D deficiency and cardiovascular pathology
Текст визуальный непосредственный
Терапевтический архив
Медицинское маркетинговое агентство "МедиаМедика"
Т. 90, Вып. 9 С. 144-150
2018
Статья
1,25(OH)2D 25(OH)D arterial hypertension atherosclerosis cardiology chronic heart failure heart rhythm disorder Vitamin D Deficiency
protective agent vitamin D cardiovascular disease heart ventricle remodeling human metabolism pathophysiology physiology risk factor vascular endothelium vitamin D deficiency Cardiovascular Diseases Endothelium, Vascular Humans Protective Agents Risk Factors Ventricular Remodeling Vitamin D Vitamin D Deficiency
Vitamin D deficiency is widespread worldwide and present in about 30-50[%] of population. In most cases, this problem is associated with musculoskeletal system pathology: Rickets in children, and osteomalacia or osteoporosis in adults. However, in recent years, convincing data was obtained on the links between Vitamin D deficiency and cardiovascular pathology. Low Vitamin D levels in humans are associated with the unfavorable cardiovascular risk factors, such as arterial hypertension (AH), diabetes mellitus, and dyslipidemia, which are the predictors of the severe cardiovascular diseases, including strokes and infarctions. It has been demonstrated that Vitamin D has a strong vasoptotective effect via endothelial dysfunction improvement, prevents blood vessels and myocardium remodeling, improves blood pressure parameters, reduces the risk of development of left ventricular hypertrophy, slows down fibrosis, reduces the risk of atherosclerosis, reduces insulin resistance, and also affects i