Longer duration of untreated psychosis is associated with poorer outcomes for patients with delusional infestation
Romanov D. V., Lepping P., Bewley A., Huber M., Freudenmann R. W., L`vov A. N., Squire S. B., Noorthoorn E. O.
Acta Dermato-Venereologica
Vol.98, Issue9, P. 848-854
Опубликовано: 2018
Тип ресурса: Статья
DOI:10.2340/00015555-2888
Аннотация:
We examined the association between the duration of untreated psychosis and outcome for patients with delusional infestation. This multi-centre international study included 211 consecutive patients. Illness severity was evaluated at first presentation and outcome was measured with the Clinical Global Impression scale (CGI) at baseline and follow-up. A regression analysis showed a clear clinical and statistically significant association between shorter duration of untreated psychosis and better outcome at follow-up. Patients with a duration of untreated psychosis of less than one year showed a CGI-S change from 5.37 to 2.07; those with a duration of untreated psychosis of 1–5 years a change from 5.48 to 2.59, and those with a duration of untreated psychosis of > 5 years a change from 5.59 to 3.37. This difference of 1.1 CGI points between the groups resembles a clinically relevant difference in patient outcome. Our results suggest that longer duration of untreated psychosis in patients
Ключевые слова:
Clinical relevance; Delusional infestation; Duration of untreated psychosis; Early intervention; Liaison psychiatry; Outcome
neuroleptic agent; adult; aged; Article; Clinical Global Impression scale; clinical outcome; cohort analysis; controlled study; delusional disorder; delusional infestation; delusional infestation; disease duration; disease severity; female; follow up; human; major clinical study; male; patient compliance; patient dropout; priority journal; psychopharmacotherapy; clinical trial; delusional parasitosis; Europe; middle aged; multicenter study; psychology; psychosis; risk factor; severity of illness index; time factor; time to treatment; treatment outcome; Adult; Aged; Delusional Parasitosis; Europe; Female; Humans; Male; Middle Aged; Psychotic Disorders; Risk Factors; Severity of Illness Index; Time Factors; Time-to-Treatment; Treatment Outcome
Язык текста: Английский
ISSN: 1651-2057
Romanov D. V. Dmitrij Vladimirovich 1980-
Lepping P.
Bewley A.
Huber M.
Freudenmann R. W.
L`vov A. N. Andrej Nikolaevich 0001-
Squire S. B.
Noorthoorn E. O.
Романов Д. В. Дмитрий Владимирович 1980-
Леппинг П.
Беwлеy А.
Хубер М.
Фреуденманн Р. W.
Львов А. Н. Андрей Николаевич 0001-
Сqуире С. Б.
Ноортхоорн Е. О.
Longer duration of untreated psychosis is associated with poorer outcomes for patients with delusional infestation
Текст визуальный непосредственный
Acta Dermato-Venereologica
Taylor & Francis Group
Vol.98, Issue9 P. 848-854
2018
Статья
Clinical relevance Delusional infestation Duration of untreated psychosis Early intervention Liaison psychiatry Outcome
neuroleptic agent adult aged Article Clinical Global Impression scale clinical outcome cohort analysis controlled study delusional disorder delusional infestation delusional infestation disease duration disease severity female follow up human major clinical study male patient compliance patient dropout priority journal psychopharmacotherapy clinical trial delusional parasitosis Europe middle aged multicenter study psychology psychosis risk factor severity of illness index time factor time to treatment treatment outcome Adult Aged Delusional Parasitosis Europe Female Humans Male Middle Aged Psychotic Disorders Risk Factors Severity of Illness Index Time Factors Time-to-Treatment Treatment Outcome
We examined the association between the duration of untreated psychosis and outcome for patients with delusional infestation. This multi-centre international study included 211 consecutive patients. Illness severity was evaluated at first presentation and outcome was measured with the Clinical Global Impression scale (CGI) at baseline and follow-up. A regression analysis showed a clear clinical and statistically significant association between shorter duration of untreated psychosis and better outcome at follow-up. Patients with a duration of untreated psychosis of less than one year showed a CGI-S change from 5.37 to 2.07; those with a duration of untreated psychosis of 1–5 years a change from 5.48 to 2.59, and those with a duration of untreated psychosis of > 5 years a change from 5.59 to 3.37. This difference of 1.1 CGI points between the groups resembles a clinically relevant difference in patient outcome. Our results suggest that longer duration of untreated psychosis in patients