Аннотация:
We report of surface modification approaches of nanoparticles with anti-Stokes luminescence, known as upconversion nanoparicles (UCNPs), comprised of inorganic host NaYF4 codoped with Yb3+ and Er3+or Tm3+. These approaches enabled the facile, lossless preparation of hybrid polymer-encapsulated UCNPs suitable for bioassays. These probes inherited UCNP properties, such as excellent photoluminescence under excitation with NIR light from the biotissue "transparency window", as well as they were dispersible in aqueous media and physiological buffers, exhibiting chemical stability. The feasibility of the hybrid UCNPs was demonstrated for in vitro bioassay and in vivo optical whole animal imaging using a home-built epiluminescence imaging system. © The Authors, published by EDP Sciences, 2018.
Generalova A.
Mironova K.
Sholina N. V. Natal`ya Valerievna 1992-
Rocheva V.
Nechaev A.
Ivukina E. A. Ekaterina Andreevna 1986-
Guller A. E. Anna Evgenyevna 1973-
Zvyagin A. V. Andrej Vasilyevich 1961-
Deev S. M. Sergej Mikhaylovich 1951-
Zubov V.
Khaydukov E. V. Evgenij Valeryevich 1984-
Генералова А.
Миронова К.
Шолина Н. В. Наталья Валериевна 1992-
Рочева В.
Нечаев А.
Ивукина Е. А. Екатерина Андреевна 1986-
Гуллер А. Е. Анна Евгеньевна 1973-
Звягин А. В. Андрей Васильевич 1961-
Деев С. М. Сергей Михайлович 1951-
Зубов В.
Хайдуков Е. В. Евгений Валерьевич 1984-
Upconversion nanoparticles: On the way from diagnostics to theranostics
Текст визуальный непосредственный
EPJ Web of Conferences
Vol.190 Num.03001
2018
Материалы конференции (Статья)
We report of surface modification approaches of nanoparticles with anti-Stokes luminescence, known as upconversion nanoparicles (UCNPs), comprised of inorganic host NaYF4 codoped with Yb3+ and Er3+or Tm3+. These approaches enabled the facile, lossless preparation of hybrid polymer-encapsulated UCNPs suitable for bioassays. These probes inherited UCNP properties, such as excellent photoluminescence under excitation with NIR light from the biotissue "transparency window", as well as they were dispersible in aqueous media and physiological buffers, exhibiting chemical stability. The feasibility of the hybrid UCNPs was demonstrated for in vitro bioassay and in vivo optical whole animal imaging using a home-built epiluminescence imaging system. © The Authors, published by EDP Sciences, 2018.