Аннотация:
Objective: High prevalence of ischemic heart disease (IHD) is currently both of medical and social concern, thus requiring treatment with drugs capable of influencing not only the prognosis of the disease but also quality of life of patients. This study was undertaken to investigate the possibilities of antianginal therapy with nicorandil and isosorbide dinitrate in order to improve quality of life of patients with stable angina pectoris. Method: The authors carried out a comprehensive examination of a total of eighty-four 44-to-76-year-old patients suffering from IHD with functional class 2-3 stable angina of effort and followed up in ambulatory settings. The patients were randomized into two groups of treatment to receive either nicorandil or isosorbide dinitrate as antianginal agents added to basic therapy. The groups of patients did not significantly differ by anamnestic and demographic characteristics. The duration of follow up amounted to 24 months. We determined the physical and
Zakharova V. L. Valeriya Leonidovna 1971-
Kozlova N. N.
Sizova Zh. M. Zhanna Mikhaylovna 1959-
Beloborodova A. V. Aleksandra Vladimirovna 1982-
Захарова В. Л. Валерия Леонидовна 1971-
Козлова Н. Н.
Сизова Ж. М. Жанна Михайловна 1959-
Белобородова А. В. Александра Владимировна 1982-
Possibilities of antianginal therapy in improvement of quality of life of patients with stable angina of effort
Текст визуальный непосредственный
Electronic Journal of General Medicine
Modestum Ltd.
Vol.15, Issue4
2018
Статья
Antianginal therapy Cognitive quality of life Nicorandil Stable angina pectoris
Objective: High prevalence of ischemic heart disease (IHD) is currently both of medical and social concern, thus requiring treatment with drugs capable of influencing not only the prognosis of the disease but also quality of life of patients. This study was undertaken to investigate the possibilities of antianginal therapy with nicorandil and isosorbide dinitrate in order to improve quality of life of patients with stable angina pectoris. Method: The authors carried out a comprehensive examination of a total of eighty-four 44-to-76-year-old patients suffering from IHD with functional class 2-3 stable angina of effort and followed up in ambulatory settings. The patients were randomized into two groups of treatment to receive either nicorandil or isosorbide dinitrate as antianginal agents added to basic therapy. The groups of patients did not significantly differ by anamnestic and demographic characteristics. The duration of follow up amounted to 24 months. We determined the physical and