Gastrectomy for Metastatic Gastric Cancer: a 15-year Experience from a Developing Country
Сахакян М. А., Gabrielyan A., Aghayan D. L., Yesayan S., Petrosyan H., Чобанян А., Kazaryan A. M., Sahakyan A. M.
Indian Journal of Surgical Oncology
Vol.10, Issue3, P. 527-534
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.1007/s13193-019-00943-4
Аннотация:
The role of surgery in the management of metastatic gastric cancer (MGC) remains unclear. The aim of this study was to investigate the surgical and oncologic outcomes of gastrectomy in patients with MGC. The study included prospectively collected data of patients with MGC operated at four medical centers in Yerevan, Armenia, between 2000 and 2014. Armenian National Center of Oncology Registry and hospital records were used to obtain survival data. Factors associated with performing gastrectomy in patients with MGC were analyzed by using the logistic regression model. The Kaplan-Meier method was applied for survival analysis, and the Cox regression model with backward selection was used for multivariate analysis. A total number of 733 patients were operated for gastric cancer including 112 (15.3[%]) with MGC. Of those, 70 underwent gastrectomy, while 42 had exploratory laparotomy or bypass. Morbidity and mortality were similar after gastrectomy and exploratory laparotomy/bypass (18.6 vs 2
Ключевые слова:
Chemotherapy; Gastrectomy; Gastric cancer; Laparotomy; Metastases
antineoplastic agent; adjuvant chemotherapy; adult; aged; Armenia; Article; cancer chemotherapy; cancer diagnosis; cancer mortality; cancer staging; cancer surgery; cancer survival; controlled study; correlational study; developing country; distant metastasis; female; follow up; gastrectomy; human; Kaplan Meier method; laparotomy; long term care; lymph node metastasis; major clinical study; male; medical record; metastasis; metastasis resection; metastatic gastric cancer; morbidity; patient satisfaction; patient selection; primary tumor; priority journal; prospective study; stomach cancer; surgical mortality; survival analysis; total stomach resection; tumor volume
Язык текста: Английский
ISSN: 0976-6952
Сахакян М. А.
Gabrielyan A.
Aghayan D. L.
Yesayan S.
Petrosyan H.
Чобанян А.
Kazaryan A. M. Ayrazat Mishikovich 1977-
Sahakyan A. M.
Sahakyan M. A.
Габриелян А.
Агхайан Д. Л.
Ьесайан С.
Петросян Х.
Chobanyan A.
Казарян А. М. Айразат Мишикович 1977-
Сахакян А. М.
Gastrectomy for Metastatic Gastric Cancer: a 15-year Experience from a Developing Country
Текст визуальный непосредственный
Indian Journal of Surgical Oncology
Vol.10, Issue3 P. 527-534
2019
Статья
Chemotherapy Gastrectomy Gastric cancer Laparotomy Metastases
antineoplastic agent adjuvant chemotherapy adult aged Armenia Article cancer chemotherapy cancer diagnosis cancer mortality cancer staging cancer surgery cancer survival controlled study correlational study developing country distant metastasis female follow up gastrectomy human Kaplan Meier method laparotomy long term care lymph node metastasis major clinical study male medical record metastasis metastasis resection metastatic gastric cancer morbidity patient satisfaction patient selection primary tumor priority journal prospective study stomach cancer surgical mortality survival analysis total stomach resection tumor volume
The role of surgery in the management of metastatic gastric cancer (MGC) remains unclear. The aim of this study was to investigate the surgical and oncologic outcomes of gastrectomy in patients with MGC. The study included prospectively collected data of patients with MGC operated at four medical centers in Yerevan, Armenia, between 2000 and 2014. Armenian National Center of Oncology Registry and hospital records were used to obtain survival data. Factors associated with performing gastrectomy in patients with MGC were analyzed by using the logistic regression model. The Kaplan-Meier method was applied for survival analysis, and the Cox regression model with backward selection was used for multivariate analysis. A total number of 733 patients were operated for gastric cancer including 112 (15.3[%]) with MGC. Of those, 70 underwent gastrectomy, while 42 had exploratory laparotomy or bypass. Morbidity and mortality were similar after gastrectomy and exploratory laparotomy/bypass (18.6 vs 2