Аннотация:
Loeffler's endocarditis remains is a very rare disease, develops due to eosinophilic inflammation predominantly of the endocardium with an outcome in fibrosis and massive thrombus formation and. He is generally characterized by an unfavorable prognosis. Clinical case of a 42-year-old patient with Loeffler endocarditis is presented. The development of the disease was preceded by a polyvalent allergy, mild dry eye syndrome and pansinusitis with a single eosinophilia of blood up to 16[%]. The reason for the hospitalization was the appearance of biventricular heart failure. During the previous year, the level of blood eosinophils remained normal, a threefold increase in the level of eosinophilic cationic protein was observed once. A 20-fold increase in the pANCA level, a 2.5-fold increase in the level of antibodies to DNA, an antibody to the nuclei of cardiomyocytes 1:160 were detected. The diagnosis was made on the basis of electrocardiography data (low QRS voltage, atrial hypertrophy), ech
Благова О. В. Ольга Владимировна 1974-
Алиьева И. Н.
Недоступ А. В. Александр Викторович 1939-
Коган Е. А. Евгения Алтаровна 1951-
Комаров Р. Н. Роман Николаевич 1977-
Чернявскy С. В.
Сеславинскайа В. В.
Шелуха П. А. Полина Александровна 1992-
Седов В. П. Всеволод Парисович 1952-
Гагарина Н. В. Нина Владимировна 1972-
Мершина Е. А.
Синицын В. Е. Валентин Евгеньевич 0001-
Фомин В. В. Виктор Викторович 1978-
Blagova O. V. Ol`ga Vladimirovna 1974-
Aliyeva I. N.
Nedostup A. V. Aleksandr Viktorovich 1939-
Kogan E. A. Evgeniya Altarovna 1951-
Komarov R. N. Roman Nikolaevich 1977-
Chernyavsky S. V.
Seslavinskaya V. V.
Shelukha P. A. Polina Aleksandrovna 1992-
Sedov V. P. Vsevolod Parisovich 1952-
Gagarina N. V. Nina Vladimirovna 1972-
Mershina E. A.
Sinitsy'n V. E. Valentin Evgenyevich 0001-
Fomin V. V. Viktor Viktorovich 1978-
Morphologically proved ANCA positive Loeffler's pancarditis: Medical and surgical treatment [Морфологически верифицированный ANCA-позитивный панкардит Лёффлера: медикаментозное и хирургическое лечение]
Morphologically proved ANCA positive Loeffler's pancarditis: Medical and surgical treatment [Морфологически верифицированный ANCA-позитивный...
Текст визуальный непосредственный
Терапевтический архив
Медицинское маркетинговое агентство "МедиаМедика"
Т. 91, Вып. 4 С. 99-106
2019
Статья
Anti-heart antibodies Antineutrophil cytoplasm antibodies Immunosuppressive therapy Left ventricular thrombosis Loeffler's endocarditis Myocardial biopsy Myocarditis Pancarditis Pericardial resection Pericarditis Restrictive cardiomyopathy Thrombectomy
azathioprine methylprednisolone neutrophil cytoplasmic antibody adult case report drug effect echocardiography electrocardiography human hypereosinophilic syndrome male myocarditis treatment outcome Adult Antibodies, Antineutrophil Cytoplasmic Azathioprine Echocardiography Electrocardiography Humans Hypereosinophilic Syndrome Male Methylprednisolone Myocarditis Treatment Outcome
Loeffler's endocarditis remains is a very rare disease, develops due to eosinophilic inflammation predominantly of the endocardium with an outcome in fibrosis and massive thrombus formation and. He is generally characterized by an unfavorable prognosis. Clinical case of a 42-year-old patient with Loeffler endocarditis is presented. The development of the disease was preceded by a polyvalent allergy, mild dry eye syndrome and pansinusitis with a single eosinophilia of blood up to 16[%]. The reason for the hospitalization was the appearance of biventricular heart failure. During the previous year, the level of blood eosinophils remained normal, a threefold increase in the level of eosinophilic cationic protein was observed once. A 20-fold increase in the pANCA level, a 2.5-fold increase in the level of antibodies to DNA, an antibody to the nuclei of cardiomyocytes 1:160 were detected. The diagnosis was made on the basis of electrocardiography data (low QRS voltage, atrial hypertrophy), ech