Phase synchronization of baroreflex oscillations of blood pressure and pulse interval in rats: The effects of cardiac autonomic blockade and...
Negulyaev V. O., Tarasova O. S., Tarasova N. V., Lukoshkova E. V., Vinogradova O. L., Borovik A. S.
Physiological Measurement
Vol.40, Issue5, Num.054003
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.1088/1361-6579/ab10d6
Аннотация:
Objective: Phase synchronization of arterial pressure (AP) and pulse interval (PI) oscillations in the low-frequency band (around 0.4 Hz in rats) is governed by baroreflex activity. In long-term stationary data recordings, such synchronization can be estimated by the coherence. The phase synchronization index (PSI) can be used as well. The aim of this study was to correlate PSI and the coherence of AP and PI under stationary conditions and to estimate the informativity of PSI as a measure of baroreflex activity during transient processes. Approach: AP and PI were recorded in conscious Wistar rats using femoral artery catheters. To study the hemodynamics during hemorrhage, blood was gradually withdrawn (20 ml kg-1 over 30 min) through a catheter in the carotid artery. Main results: PSI and coherence spectra calculated from 30-minute AP and PI recordings demonstrated distinct peaks at the frequency of 0.4 Hz; these indicators correlate well with each other (Pearson r = 0.920, p < 0.00
Ключевые слова:
atenolol; baroreflex; cross-spectral analysis; hemodynamic variability; hypovolemia; methylatropine; phase synchronization
animal; autonomic nervous system; bleeding; blood pressure; heart; male; pathophysiology; physiology; pressoreceptor reflex; pulse rate; Wistar rat; Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Heart; Hemorrhage; Male; Pulse; Rats, Wistar
Язык текста: Английский
ISSN: 1361-6579
Negulyaev V. O.
Tarasova O. S.
Tarasova N. V. Nadezhda Valeryevna 1982-
Lukoshkova E. V.
Vinogradova O. L.
Borovik A. S.
Негуляев В. О.
Тарасова О. С.
Тарасова Н. В. Надежда Валерьевна 1982-
Лукошкова Е. В.
Виноградова О. Л.
Боровик А. С.
Phase synchronization of baroreflex oscillations of blood pressure and pulse interval in rats: The effects of cardiac autonomic blockade and gradual blood loss
Phase synchronization of baroreflex oscillations of blood pressure and pulse interval in rats: The effects of cardiac autonomic blockade and...
Текст визуальный непосредственный
Physiological Measurement
Institute of Physics and IOP Publishing Limited
Vol.40, Issue5 Num.054003
2019
Статья
atenolol baroreflex cross-spectral analysis hemodynamic variability hypovolemia methylatropine phase synchronization
animal autonomic nervous system bleeding blood pressure heart male pathophysiology physiology pressoreceptor reflex pulse rate Wistar rat Animals Autonomic Nervous System Baroreflex Blood Pressure Heart Hemorrhage Male Pulse Rats, Wistar
Objective: Phase synchronization of arterial pressure (AP) and pulse interval (PI) oscillations in the low-frequency band (around 0.4 Hz in rats) is governed by baroreflex activity. In long-term stationary data recordings, such synchronization can be estimated by the coherence. The phase synchronization index (PSI) can be used as well. The aim of this study was to correlate PSI and the coherence of AP and PI under stationary conditions and to estimate the informativity of PSI as a measure of baroreflex activity during transient processes. Approach: AP and PI were recorded in conscious Wistar rats using femoral artery catheters. To study the hemodynamics during hemorrhage, blood was gradually withdrawn (20 ml kg-1 over 30 min) through a catheter in the carotid artery. Main results: PSI and coherence spectra calculated from 30-minute AP and PI recordings demonstrated distinct peaks at the frequency of 0.4 Hz; these indicators correlate well with each other (Pearson r = 0.920, p < 0.00