Halloysite nanotubes loaded with alkyl trimethyl ammonium bromide as antibacterial agent for root canal sealers
Monteiro J. C., Garcia I. M., Leitune V. C. B., Visioli F., de S. B. G., Samuel S. M. W., Makeeva I. M., Collares F. M., Sauro S.
Dental Materials
Vol.35, Issue5, P. 789-796
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.1016/j.dental.2019.02.018
Аннотация:
Objective: This study aimed at evaluating the effects of experimental endodontic sealers containing halloysite nanotubes (HNT) doped with alkyl trimethyl ammonium bromide (ATAB). Methods: An experimental dual-cure resin sealer was formulated and used as control material. This resin was also filled with ATAB and HNT at different ratios (GATAB:HNT 1:1; 1:2; 2:1) generate three experimental resin sealers. The ATAB:HNT filler was characterized through transmission electron microscopy (TEM). While, the experimental and control sealers were evaluated for degree of conversion, softening ration, radiopacity, flow, film thickness, antibacterial activity for biofilm and planktonic bacteria and cytotoxicity in human pulpal cells. Results: GATAB:HNT (1:1) significantly increased the immediate DC (p < 0.05), although no difference was encountered between the groups after 24 h (p > 0.05). All the experimental cements (ATAB/HNT) showed relatively low initial Knoop hardness (p < 0.05), but wi
Ключевые слова:
Ammonium compounds; Antibacterial; Chemomechanical properties; Drug delivery system; Root canal sealers
Ammonium compounds; Biofilms; Biomechanics; Cements; Film thickness; High resolution transmission electron microscopy; Hydraulic structures; Kaolinite; Mechanical properties; Nanotubes; Resins; Yarn; Anti-bacterial activity; Antibacterial; Chemomechanical; Degree of conversion; Drug delivery system; Halloysite nanotubes; Root canal sealers; Through transmission; Controlled drug delivery; ammonium bromide; antiinfective agent; bromide; nanotube; quaternary ammonium derivative; root canal filling material; clay; dental pulp cavity; human; materials testing; Anti-Bacterial Agents; Bromides; Clay; Dental Pulp Cavity; Humans; Materials Testing; Nanotubes; Quaternary Ammonium Compounds; Root Canal Filling Materials
Язык текста: Английский
ISSN: 1879-0097
Monteiro J. C.
Garcia I. M.
Leitune V. C. B.
Visioli F.
de S. B. G. Souza Balbinot G.
Samuel S. M. W.
Makeeva I. M. Irina Mikhaylovna 1963-
Collares F. M.
Sauro S. Sal`vatore 1977-
Монтеиро Й. C.
Гарcиа И. М.
Леитюне В. C. Б.
Висиоли Ф.
де С. Б. Г. Соуза Балбинот Г.
Самуел С. М. W.
Макеева И. М. Ирина Михайловна 1963-
Cолларес Ф. М.
Сауро С. Сальваторе 1977-
Halloysite nanotubes loaded with alkyl trimethyl ammonium bromide as antibacterial agent for root canal sealers
Текст визуальный непосредственный
Dental Materials
Elsevier Science Publisher B.V.
Vol.35, Issue5 P. 789-796
2019
Статья
Ammonium compounds Antibacterial Chemomechanical properties Drug delivery system Root canal sealers
Ammonium compounds Biofilms Biomechanics Cements Film thickness High resolution transmission electron microscopy Hydraulic structures Kaolinite Mechanical properties Nanotubes Resins Yarn Anti-bacterial activity Antibacterial Chemomechanical Degree of conversion Drug delivery system Halloysite nanotubes Root canal sealers Through transmission Controlled drug delivery ammonium bromide antiinfective agent bromide nanotube quaternary ammonium derivative root canal filling material clay dental pulp cavity human materials testing Anti-Bacterial Agents Bromides Clay Dental Pulp Cavity Humans Materials Testing Nanotubes Quaternary Ammonium Compounds Root Canal Filling Materials
Objective: This study aimed at evaluating the effects of experimental endodontic sealers containing halloysite nanotubes (HNT) doped with alkyl trimethyl ammonium bromide (ATAB). Methods: An experimental dual-cure resin sealer was formulated and used as control material. This resin was also filled with ATAB and HNT at different ratios (GATAB:HNT 1:1; 1:2; 2:1) generate three experimental resin sealers. The ATAB:HNT filler was characterized through transmission electron microscopy (TEM). While, the experimental and control sealers were evaluated for degree of conversion, softening ration, radiopacity, flow, film thickness, antibacterial activity for biofilm and planktonic bacteria and cytotoxicity in human pulpal cells. Results: GATAB:HNT (1:1) significantly increased the immediate DC (p < 0.05), although no difference was encountered between the groups after 24 h (p > 0.05). All the experimental cements (ATAB/HNT) showed relatively low initial Knoop hardness (p < 0.05), but wi