Extracellular matrix collagen fiber structures of the gastrointestinal connective tissues in mice after a 30 day orbital flight
Атиакшин Д. А., Алехеева Н. Т., Клочкова С. В., Никитюк Д. Б.
Вопросы питания
Т. 88, Вып. 1, С. 26-40
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.24411/0042-8833-2019-10003
Аннотация:
The organs of the digestive system experience high sensitivity to the orbital flight factors and may limit the implementation of the professional activities of crews on International space station. The connective tissue as a system-forming matrix of the integrative and buffering metabolic environment has a particular importance in the space biomedicine because it provides the inner organ functionality in the conditions of changing level of the gravitational incentive. Aim-to study the adaptive mechanisms of the fibrous component of the extracellular matrix of the connective tissue of stomach and intestines on the effect of prolonged microgravity. Material and methods. Using histochemical methods the condition of collagen fibers of a specific tissue microenvironment of the membranes of stomach and intestines of C57BL/6N mice (58 males with an initial body weight of 27.1 ±0.7 g) after a 30-day space flight and the following 7-day land readaptation was studied as well as in the animals re
Ключевые слова:
C57BL/6Nmice; Collagen fibers; Connective tissue; Digestive system; Orbital flight; Zero gravity
collagen; animal; connective tissue; extracellular matrix; intestine; male; metabolism; mouse; space flight; stomach; time factor; Animals; Collagen; Connective Tissue; Extracellular Matrix; Intestines; Male; Mice; Space Flight; Stomach; Time Factors
Язык текста: Русский
ISSN: 0042-8833
Атиакшин Д. А.
Алехеева Н. Т.
Клочкова С. В. Светлана Валерьевна 1968-
Никитюк Д. Б. Дмитрий Борисович 1962-
Atiakshin D. A.
Alexeeva N. T.
Klochkova S. V. Svetlana Valeryevna 1968-
Nikituk D. B. Dmitrij Borisovich 1962-
Extracellular matrix collagen fiber structures of the gastrointestinal connective tissues in mice after a 30 day orbital flight
Текст визуальный непосредственный
Вопросы питания
Издательская группа "ГЭОТАР-Медиа"
Т. 88, Вып. 1 С. 26-40
2019
Статья
C57BL/6Nmice Collagen fibers Connective tissue Digestive system Orbital flight Zero gravity
collagen animal connective tissue extracellular matrix intestine male metabolism mouse space flight stomach time factor Animals Collagen Connective Tissue Extracellular Matrix Intestines Male Mice Space Flight Stomach Time Factors
The organs of the digestive system experience high sensitivity to the orbital flight factors and may limit the implementation of the professional activities of crews on International space station. The connective tissue as a system-forming matrix of the integrative and buffering metabolic environment has a particular importance in the space biomedicine because it provides the inner organ functionality in the conditions of changing level of the gravitational incentive. Aim-to study the adaptive mechanisms of the fibrous component of the extracellular matrix of the connective tissue of stomach and intestines on the effect of prolonged microgravity. Material and methods. Using histochemical methods the condition of collagen fibers of a specific tissue microenvironment of the membranes of stomach and intestines of C57BL/6N mice (58 males with an initial body weight of 27.1 ±0.7 g) after a 30-day space flight and the following 7-day land readaptation was studied as well as in the animals re