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Role of mycoplasma infection in acute bronchial asthma in children

Горина Л. Г., Крылова Н. А., Гончарова С. А., Раковская И. В., Бархатова О. И.
Инфекционные болезни
Т. 16, Вып. 4, С. 16-21
Опубликовано: 2018
Тип ресурса: Статья

DOI:10.20953/1729-9225-2018-4-16-21

Аннотация:
The objective. To specify the duration of persistence of antigens and DNA of Mycoplasma pneumoniae (M. pneumoniae) and Mycoplasma hominis (M. hominis) cells in the free state and as part of circulating immune complexes in blood of children suffering from bronchial asthma. Patients and methods. In the University Children’s Clinical Hospital of the Sechenov University, 161 children aged 1 to 14 years were observed. Group 1 (treatment group) included 126 children with bronchial asthma. 55 children (43.7[%]) had a mild course of disease, 52 children – moderate (42.1[%]) and 19 children (15.1[%]) – severe. All children were in the exacerbation period. Group 2 (control) consisted of 35 children with ARVI. The mean age of children in group 1 – 5.4 ± 1.8 years (79 boys (62.7[%]) and 47 girls (37.3[%])); in group 2 – 5.7 ± 1.9 years (20 boys (57.1[%]) and 15 girls (42.9[%]). Diagnostic methods used: cultivation of mycoplasmas, preparation of immune serums, aggregate-haemagglutination assays (AHAA), polymeras
Ключевые слова:
Antibodies; Antigens; Bronchial asthma; DNA; Mini-colonies; Mycoplasms
Язык текста: Русский
ISSN: 2414-9691
Горина Л. Г.
Крылова Н. А. Наталия Алексеевна 1962-
Гончарова С. А. Светлана Анатольевна 1961-
Раковская И. В. Ирина Валентиновна 1935-
Бархатова О. И.
Gorina L. G.
Kry'lova N. A. Nataliya Alekseevna 1962-
Goncharova S. A. Svetlana Anatolyevna 1961-
Rakovskaya I. V. Irina Valentinovna 1935-
Barkhatova O. I.
Role of mycoplasma infection in acute bronchial asthma in children
Текст визуальный непосредственный
Инфекционные болезни
ООО "Издательство "Династия"
Т. 16, Вып. 4 С. 16-21
2018
Статья
Antibodies Antigens Bronchial asthma DNA Mini-colonies Mycoplasms
The objective. To specify the duration of persistence of antigens and DNA of Mycoplasma pneumoniae (M. pneumoniae) and Mycoplasma hominis (M. hominis) cells in the free state and as part of circulating immune complexes in blood of children suffering from bronchial asthma. Patients and methods. In the University Children’s Clinical Hospital of the Sechenov University, 161 children aged 1 to 14 years were observed. Group 1 (treatment group) included 126 children with bronchial asthma. 55 children (43.7[%]) had a mild course of disease, 52 children – moderate (42.1[%]) and 19 children (15.1[%]) – severe. All children were in the exacerbation period. Group 2 (control) consisted of 35 children with ARVI. The mean age of children in group 1 – 5.4 ± 1.8 years (79 boys (62.7[%]) and 47 girls (37.3[%])); in group 2 – 5.7 ± 1.9 years (20 boys (57.1[%]) and 15 girls (42.9[%]). Diagnostic methods used: cultivation of mycoplasmas, preparation of immune serums, aggregate-haemagglutination assays (AHAA), polymeras