Effect of the mixed herbal medicines extracts on menopausal symptoms: A randomized clinical trial study
Minenko I. A., Berihanova R. R., Shakhmatova S. A.
Electronic Journal of General Medicine
Vol.16, Issue3, Num.em137
Опубликовано: 2019
Тип ресурса: Статья
Аннотация:
Background: Menopause cause many symptoms, which may impair quality of life the women. The study aims to determine the effectiveness of mixed herbal medicinal extracts on menopausal symptoms. Method: A randomized, triple-blind, placebo-controlled clinical trial was conducted on 120 peri-menopausal women for 12 weeks. All participants took herbal extracts drops orally daily. They were randomly allocated into four groups: placebo (C), A (250 mg chamomile, 30 mg fennel, 15 mg saffron), B (1000 mg chamomile, 120 mg fennel, 60 mg saffron), and D (500 mg chamomile, 60 mg fennel, 30 mg saffron).They completed a demographic and MRS questionnaire at week 0, 6.12. Result: 108 participants successfully completed the assessment. No significant differences in demographic variables were seen between the four groups. The median MRS score was significantly reduced in group B from 27.5±3 to 7.5±5. In group D, it was significantly reduced from 29±12 to 22±9.25The effect size in this study was 0.92. Conc
Ключевые слова:
Alternative medicine; Herbal medicine; Menopause
chamomile; fennel extract; placebo; plant extract; saffron extract; unclassified drug; adult; Article; body mass; controlled study; drug efficacy; drug megadose; drug withdrawal; female; fennel; herbal medicine; human; low drug dose; major clinical study; medicinal plant; menopause; menopause related disorder; middle aged; premenopause; quality of life; questionnaire; randomized controlled trial; skin redness; triple blind procedure
Язык текста: Английский
ISSN: 2516-3507
Minenko I. A. Inessa Anatolyevna 1967-
Berihanova R. R.
Shakhmatova S. A.
Миненко И. А. Инесса Анатольевна 1967-
Бериханова Р. Р.
Шахматова С. А.
Effect of the mixed herbal medicines extracts on menopausal symptoms: A randomized clinical trial study
Текст визуальный непосредственный
Electronic Journal of General Medicine
Modestum Ltd.
Vol.16, Issue3 Num.em137
2019
Статья
Alternative medicine Herbal medicine Menopause
chamomile fennel extract placebo plant extract saffron extract unclassified drug adult Article body mass controlled study drug efficacy drug megadose drug withdrawal female fennel herbal medicine human low drug dose major clinical study medicinal plant menopause menopause related disorder middle aged premenopause quality of life questionnaire randomized controlled trial skin redness triple blind procedure
Background: Menopause cause many symptoms, which may impair quality of life the women. The study aims to determine the effectiveness of mixed herbal medicinal extracts on menopausal symptoms. Method: A randomized, triple-blind, placebo-controlled clinical trial was conducted on 120 peri-menopausal women for 12 weeks. All participants took herbal extracts drops orally daily. They were randomly allocated into four groups: placebo (C), A (250 mg chamomile, 30 mg fennel, 15 mg saffron), B (1000 mg chamomile, 120 mg fennel, 60 mg saffron), and D (500 mg chamomile, 60 mg fennel, 30 mg saffron).They completed a demographic and MRS questionnaire at week 0, 6.12. Result: 108 participants successfully completed the assessment. No significant differences in demographic variables were seen between the four groups. The median MRS score was significantly reduced in group B from 27.5±3 to 7.5±5. In group D, it was significantly reduced from 29±12 to 22±9.25The effect size in this study was 0.92. Conc