Аннотация:
Objective: to study potantial of remote ischemic preconditioning (RIP) as method of cardioprotection during coronary artery bypass surgery with cardiopulmonary bypass (CPB) and anesthesia with propofol. Materials and methods. We included in this study 87 patients (7 were excluded) with ischemic heart disease, hospitalized in the clinic of aortic and cardiovascular surgery of the I. M. Sechenov First Moscow State Medical University clinical hospital № 1. All patients had indications for direct myocardial revascularization by coronary artery bypass surgery. One day before operation patients were randomly assigned to 2 groups depending on preparation scheme: main group of RIP and the control group. The frequency of complications during surgery and in the postoperative period was assessed. Troponin I level was measured before, and in 2 and 24 hours after surgery. The level of lactate in the venous blood was measured before and after surgery. Results. Numbers of intraoperative and early pos
Ключевые слова:
Coronary artery bypass; Intraoperative complications prevention; Remote ischemic preconditioning
propofol; troponin I; anesthesia; cardiopulmonary bypass; controlled study; coronary artery bypass graft; human; ischemic preconditioning; lower limb; randomized controlled trial; Russian Federation; Anesthesia; Cardiopulmonary Bypass; Coronary Artery Bypass; Humans; Ischemic Preconditioning; Lower Extremity; Moscow; Propofol; Troponin I
Тютер Д. С.
Комаров Р. Н. Роман Николаевич 1977-
Гласачев О. С.
Сыркин А. Л. Абрам Львович 1930-
Северова Л. П. Людмила Петровна 1992-
Иванова Е. В.
Ломоносова А. А.
Копылов Ф. Ю. Филипп Юрьевич 1976-
Tuter D. S.
Komarov R. N. Roman Nikolaevich 1977-
Glasachev O. S.
Sy'rkin A. L. Abram L`vovich 1930-
Severova L. P. Lyudmila Petrovna 1992-
Ivanova E. V.
Lomonosova A. A.
Kopy'lov F. Yu. Filipp Yuryevich 1976-
Remote ischemic preconditioning with the use of lower limb before coronary artery bypass surgery with cardiopulmonary bypass and anesthesia with propofol [Дистантное ишемическое прекондиционирование с использованием нижней конечности перед шунтированием коронарных артерий в условиях искусственного кровообращения и анестезии, включающей пропофол]
Remote ischemic preconditioning with the use of lower limb before coronary artery bypass surgery with cardiopulmonary bypass and anesthesia with...
Текст визуальный непосредственный
Кардиология
Общество специалистов по сердечной недостаточности
Т. 59, Вып. 2 С. 38-44
2018
Статья
Coronary artery bypass Intraoperative complications prevention Remote ischemic preconditioning
propofol troponin I anesthesia cardiopulmonary bypass controlled study coronary artery bypass graft human ischemic preconditioning lower limb randomized controlled trial Russian Federation Anesthesia Cardiopulmonary Bypass Coronary Artery Bypass Humans Ischemic Preconditioning Lower Extremity Moscow Propofol Troponin I
Objective: to study potantial of remote ischemic preconditioning (RIP) as method of cardioprotection during coronary artery bypass surgery with cardiopulmonary bypass (CPB) and anesthesia with propofol. Materials and methods. We included in this study 87 patients (7 were excluded) with ischemic heart disease, hospitalized in the clinic of aortic and cardiovascular surgery of the I. M. Sechenov First Moscow State Medical University clinical hospital № 1. All patients had indications for direct myocardial revascularization by coronary artery bypass surgery. One day before operation patients were randomly assigned to 2 groups depending on preparation scheme: main group of RIP and the control group. The frequency of complications during surgery and in the postoperative period was assessed. Troponin I level was measured before, and in 2 and 24 hours after surgery. The level of lactate in the venous blood was measured before and after surgery. Results. Numbers of intraoperative and early pos