Taurin influence on clinical course of stable angina in postinfarction cardiosclerosis patients
Василиева И. С., Резван В. В.
Российский кардиологический журнал
Т. 2018, Вып. 4, С. 82-88
Опубликовано: 2018
Тип ресурса: Статья
DOI:10.15829/1560-4071-2018-4-82-88
Аннотация:
Aim. Study of efficacy and safety of taurin in management of stable angina patients with postinfarction cardiosclerosis. Material and methods. Totally, 95 postinfarction cardiosclerosis patients included, with stable angina of II and III functional class. The patients that were included, had refused revascularization. To the main group, 48 were included with added taurin (Dibicor, “PIK-Pharma”, Russia, 750 mg daily), and to comparison group — 47 patients that were taking standard treatment and placebo. Treatment duration 3 months. Results. Clinical efficacy of taurin in postinfarction cardiosclerosis and stable angina is confirmed by significant improvement of the following parameters: subjective state (decreased fatigue, less complaints on palpitation, less severity of dyspnea and rarer angina attacks), of the life quality parameters by Seattle questionnaire; echocardiographic parameters, normalized cardiac rhythm. Postive changes achieved on the basis therapy with taurin, remained fo
Ключевые слова:
Cardiac dysrhythmias; Exercise tolerance; Life quality; Postinfarction cardiosclerosis; Stable angina; Taurin
dibicor; taurine; Article; controlled study; disease course; disease severity; drug efficacy; drug safety; dyspnea; fatigue; heart muscle fibrosis; heart palpitation; heart rhythm; human; major clinical study; postinfarction cardiosclerosis; postinfarction cardiosclerosis; prescription; quality of life; stable angina pectoris; treatment duration
Язык текста: Русский
ISSN: 2618-7620
Василиева И. С.
Резван В. В. Владимир Владимирович 1964-
Vasilieva I. S.
Rezvan V. V. Vladimir Vladimirovich 1964-
Taurin influence on clinical course of stable angina in postinfarction cardiosclerosis patients
Текст визуальный непосредственный
Российский кардиологический журнал
ООО "Силицея-Полиграф"
Т. 2018, Вып. 4 С. 82-88
2018
Статья
Cardiac dysrhythmias Exercise tolerance Life quality Postinfarction cardiosclerosis Stable angina Taurin
dibicor taurine Article controlled study disease course disease severity drug efficacy drug safety dyspnea fatigue heart muscle fibrosis heart palpitation heart rhythm human major clinical study postinfarction cardiosclerosis postinfarction cardiosclerosis prescription quality of life stable angina pectoris treatment duration
Aim. Study of efficacy and safety of taurin in management of stable angina patients with postinfarction cardiosclerosis. Material and methods. Totally, 95 postinfarction cardiosclerosis patients included, with stable angina of II and III functional class. The patients that were included, had refused revascularization. To the main group, 48 were included with added taurin (Dibicor, “PIK-Pharma”, Russia, 750 mg daily), and to comparison group — 47 patients that were taking standard treatment and placebo. Treatment duration 3 months. Results. Clinical efficacy of taurin in postinfarction cardiosclerosis and stable angina is confirmed by significant improvement of the following parameters: subjective state (decreased fatigue, less complaints on palpitation, less severity of dyspnea and rarer angina attacks), of the life quality parameters by Seattle questionnaire; echocardiographic parameters, normalized cardiac rhythm. Postive changes achieved on the basis therapy with taurin, remained fo