Health-Related Quality of Life in Children and Adults with Primary Immunodeficiencies: A Systematic Review and Meta-Analysis
Peshko D. A., Kulbachinskaya E., Korsunskij I. A., Kondrikova E. V., Pulvirenti F., Quinti I., Blyuss O., Dunn G. A., Munblit D. B.
Journal of Allergy and Clinical Immunology: In Practice
Vol.7, Issue6, P. 1929-1957.e5
Опубликовано: 2019
Тип ресурса: Статья
DOI:10.1016/j.jaip.2019.02.013
Аннотация:
Background: Primary immunodeficiency diseases (PIDs) are a group of diseases that have been found to have an adverse impact on quality of life and health-related quality of life (HRQOL). Objective: To systematically assess available evidence on the HRQOL of patients with PID. Methods: We performed a literature search of all studies reporting HRQOL assessments in patients with PID published in English from inception to April 11, 2017, using MEDLINE and EMBASE. Results: Of 1699 articles, 37 met the inclusion criteria. HRQOL was assessed by using various generic instruments. Child Health Questionnaire - Parent Form 50 and short-form 36 were the most frequently used (for children and adults, respectively). No PID-specific HRQOL instruments were used for children. HRQOL is significantly lower in adults with PID (mean score difference, −24.46; 95[%] CI, −34.57 to −14.34) and children (−10.06; 95[%] CI, −12.95 to −7.17) compared with the reference population and lower than in patients with other
Ключевые слова:
Health-related quality of life; PID; Primary immunodeficiency diseases; quality of life; Systematic review
adult; Article; child; Child Health Questionnaire Parent Form 50; clinical feature; data base; diabetes mellitus; evidence based practice; human; immune deficiency; juvenile rheumatoid arthritis; population risk; psychological well-being; quality of life; questionnaire; risk factor; self report; Short Form 36; systematic review
Язык текста: Английский
ISSN: 2213-2201
Peshko D. A. Dmitrij Alekseevich 1995-
Kulbachinskaya E.
Korsunskij I. A. Il`ya Anatolyevich 1982-
Kondrikova E. V. Elena Vladimirovna 1978-
Pulvirenti F.
Quinti I.
Blyuss O. Oleg 1985-
Dunn G. A. Galvin A.
Munblit D. B. Daniil Borisovich 1980-
Пешко Д. А. Дмитрий Алексеевич 1995-
Кулбачинскайа Е.
Корсунский И. А. Илья Анатольевич 1982-
Кондрикова Е. В. Елена Владимировна 1978-
Пулвиренти Ф.
Qуинти И.
Блюсс О. Олег 1985-
Дунн Г. А. Галвин А.
Мунблит Д. Б. Даниил Борисович 1980-
Health-Related Quality of Life in Children and Adults with Primary Immunodeficiencies: A Systematic Review and Meta-Analysis
Текст визуальный непосредственный
Journal of Allergy and Clinical Immunology: In Practice
Vol.7, Issue6 P. 1929-1957.e5
2019
Статья
Health-related quality of life PID Primary immunodeficiency diseases quality of life Systematic review
adult Article child Child Health Questionnaire Parent Form 50 clinical feature data base diabetes mellitus evidence based practice human immune deficiency juvenile rheumatoid arthritis population risk psychological well-being quality of life questionnaire risk factor self report Short Form 36 systematic review
Background: Primary immunodeficiency diseases (PIDs) are a group of diseases that have been found to have an adverse impact on quality of life and health-related quality of life (HRQOL). Objective: To systematically assess available evidence on the HRQOL of patients with PID. Methods: We performed a literature search of all studies reporting HRQOL assessments in patients with PID published in English from inception to April 11, 2017, using MEDLINE and EMBASE. Results: Of 1699 articles, 37 met the inclusion criteria. HRQOL was assessed by using various generic instruments. Child Health Questionnaire - Parent Form 50 and short-form 36 were the most frequently used (for children and adults, respectively). No PID-specific HRQOL instruments were used for children. HRQOL is significantly lower in adults with PID (mean score difference, −24.46; 95[%] CI, −34.57 to −14.34) and children (−10.06; 95[%] CI, −12.95 to −7.17) compared with the reference population and lower than in patients with other