Hypolipidemic therapy in stroke prevention: Existing standards, evidence-based medicine data and real practice
Гаисенок О. В., Рожков А. Н., Лишута А. С.
Рациональная фармакотерапия в кардиологии
Т. 14, Вып. 3, С. 434-440
Опубликовано: 2018
Тип ресурса: Статья
DOI:10.20996/1819-6446-2018-14-3-434-440
Аннотация:
Cardiovascular diseases occupy a leading position in morbidity, mortality and disability in most countries. Ischemic heart disease and stroke lead in the structure of mortality from cardiovascular diseases. The issues of lipid-lowering therapy with statins in the aspect of stroke prevention are discussed in the article. The main risk factors of atherosclerosis and their prevalence are presented. Topical standards for statin use, evidence-based medicine data obtained in randomized clinical trials, and evidence from actual clinical practice are covered. Possible promising areas of statin use for the prevention of acute cerebrovascular accident are also considered. Combination therapy together with other lipid-lowering drugs, as well as drugs of other pharmacological groups, the use of statins from earlier ages, the practical implementation of pleiotropic effects of statins can be attributed to the latter. The authors clearly demonstrate that the actual practice of using statins lags sign
Ключевые слова:
Evidence-based medicine; Lipid-lowering therapy; Real practice; Statins; Stroke
hydroxymethylglutaryl coenzyme A reductase inhibitor; Article; atherosclerosis; cardiovascular disease; cerebrovascular accident; clinical practice; drug efficacy; evidence based medicine; human; medication compliance; patient attitude; pleiotropy; practice guideline; preventive medicine
Язык текста: Русский
ISSN: 2225-3653
Гаисенок О. В.
Рожков А. Н.
Лишута А. С. Алексей Сергеевич 1976-
Gaisenok O. V.
Rozhkov A. N.
Lishuta A. S. Aleksej Sergeevich 1976-
Hypolipidemic therapy in stroke prevention: Existing standards, evidence-based medicine data and real practice
Текст визуальный непосредственный
Рациональная фармакотерапия в кардиологии
Столичная издательская компания
Т. 14, Вып. 3 С. 434-440
2018
Статья
Evidence-based medicine Lipid-lowering therapy Real practice Statins Stroke
hydroxymethylglutaryl coenzyme A reductase inhibitor Article atherosclerosis cardiovascular disease cerebrovascular accident clinical practice drug efficacy evidence based medicine human medication compliance patient attitude pleiotropy practice guideline preventive medicine
Cardiovascular diseases occupy a leading position in morbidity, mortality and disability in most countries. Ischemic heart disease and stroke lead in the structure of mortality from cardiovascular diseases. The issues of lipid-lowering therapy with statins in the aspect of stroke prevention are discussed in the article. The main risk factors of atherosclerosis and their prevalence are presented. Topical standards for statin use, evidence-based medicine data obtained in randomized clinical trials, and evidence from actual clinical practice are covered. Possible promising areas of statin use for the prevention of acute cerebrovascular accident are also considered. Combination therapy together with other lipid-lowering drugs, as well as drugs of other pharmacological groups, the use of statins from earlier ages, the practical implementation of pleiotropic effects of statins can be attributed to the latter. The authors clearly demonstrate that the actual practice of using statins lags sign