Аннотация:
Aim. To evaluate a complex clinical efficacy, tolerability and safety of statin drugs - simvastatin, atorvastatin, rosuvastatin in patients with hyperlipidemia (HL). Material and methods. The assessment of clinical efficacy was done in 90 patients with HL and arterial hypertension of the grades 1 and 2, age 40-75 y.o.; some of them had coronary heart disease. Results. In 90 patients with cardiac pathology and HL, selected to 3 groups by 30 persons, the clinical efficacy of the listed statins was assessed. A significant hypolipidemic effect was noted as a decline of atherogenicity of the blood, with slight more prominent effect of rosuvastatin. Conclusion. The data makes it to conclude the simvastatin, atorvastatin and rosuvastatin are equally effective hypolipidemic drugs in HL type IIA and IIB patients. The time frame, type and grade of positive changes in lipid profile are almost the same, and in rosuvastatin just slightly more prominent. © 2018 Vserossiiskoe Obshchestvo Kardiologov.
Сивков А. С. Андрей Сергеевич 1973-
Ших Е. В.
Осадчук М. А. Михаил Алексеевич 1951-
Сивкова С. К. Светлана Константиновна 1950-
Киреева Н. В. Наталья Викторовна 1976-
Чернусь Н. П. Наталья Павловна 1956-
Sivkov A. S. Andrej Sergeevich 1973-
Shih E. V.
Osadchuk M. A. Mikhail Alekseevich 1951-
Sivkova S. K. Svetlana Konstantinovna 1950-
Kireeva N. V. Natal`ya Viktorovna 1976-
Chernus` N. P. Natal`ya Pavlovna 1956-
Complex assessment of efficacy of statins prescribed at most by clinicians
Текст визуальный непосредственный
Кардиоваскулярная терапия и профилактика
ООО "Силицея-Полиграф"
Т. 17, Вып. 3 С. 22-26
2018
Статья
Hyperlipidemia Statins
Aim. To evaluate a complex clinical efficacy, tolerability and safety of statin drugs - simvastatin, atorvastatin, rosuvastatin in patients with hyperlipidemia (HL). Material and methods. The assessment of clinical efficacy was done in 90 patients with HL and arterial hypertension of the grades 1 and 2, age 40-75 y.o.; some of them had coronary heart disease. Results. In 90 patients with cardiac pathology and HL, selected to 3 groups by 30 persons, the clinical efficacy of the listed statins was assessed. A significant hypolipidemic effect was noted as a decline of atherogenicity of the blood, with slight more prominent effect of rosuvastatin. Conclusion. The data makes it to conclude the simvastatin, atorvastatin and rosuvastatin are equally effective hypolipidemic drugs in HL type IIA and IIB patients. The time frame, type and grade of positive changes in lipid profile are almost the same, and in rosuvastatin just slightly more prominent. © 2018 Vserossiiskoe Obshchestvo Kardiologov.