Аннотация:
Long-acting bronchodilators (long-acting β2-agonists (LABA), long-acting anticholinergics (LAMA) and their combinations) are the basic drugs for treatment of stable chronic obstructive pulmonary disease (COPD). Indacaterol/glycopyrronium (IND/GLY) is the first fixed LABA/LAMA combination acquired significant evidence of its efficacy for improvement lung function, symptoms, and quality of life, and decrease in the rate of acute exacerbations of COPD. The aim of this review was to reassess clinical efficacy of IND/GLY in treatment of COPD with regard to recent data and to outline the further role of this combination in therapy of COPD. © 2018 Medical Education. All rights reserved.
Ключевые слова:
Cardiovascular system; Chronic obstructive pulmonary disease; Dual bronchodilation; Indacaterol/glycopyrronium; Lung hyperinflation; Remodeling
glycopyrronium bromide plus indacaterol; chronic obstructive lung disease; combination drug therapy; drug efficacy; Review
Авдеев С. Н. Сергей Николаевич 1968-
Трушенко Н. В. Наталья Владимировна 1984-
Avdeev S. N. Sergej Nikolaevich 1968-
Trushenko N. V. Natal`ya Vladimirovna 1984-
Effects of fixed combination of indacaterol/glycopyrronium in chronic obstructive pulmonary disease: State-of-the art review
Текст визуальный непосредственный
Пульмонология
Научно-практический журнал "Пульмонология"
Т. 28, Вып. 2 С. 224-233
2018
Обзор
Cardiovascular system Chronic obstructive pulmonary disease Dual bronchodilation Indacaterol/glycopyrronium Lung hyperinflation Remodeling
glycopyrronium bromide plus indacaterol chronic obstructive lung disease combination drug therapy drug efficacy Review
Long-acting bronchodilators (long-acting β2-agonists (LABA), long-acting anticholinergics (LAMA) and their combinations) are the basic drugs for treatment of stable chronic obstructive pulmonary disease (COPD). Indacaterol/glycopyrronium (IND/GLY) is the first fixed LABA/LAMA combination acquired significant evidence of its efficacy for improvement lung function, symptoms, and quality of life, and decrease in the rate of acute exacerbations of COPD. The aim of this review was to reassess clinical efficacy of IND/GLY in treatment of COPD with regard to recent data and to outline the further role of this combination in therapy of COPD. © 2018 Medical Education. All rights reserved.