Аннотация:
Aim. Evaluation of clinical specifics, predictors of repeat hospitalizations and mortality in chronic obstructive pulmonary disease (COPD) patients according to pulmonary hypertension (PH) severity grade. Material and methods. To the study, 288 COPD patients included (II-IV severity grade, GOLD 2016; males 276, females 12; mean age 59,5±9,27 y. o., smoking 23,1±11,42 pack/years; 2,4±0,89 exacerbations annually, body mass index (BMI) 27,2±12,06 kg/m2). According to the presence and grade of systolic pressure increase in pulmonary artery (SPPA) the patients were selected to three groups: 1st — with no PH (SPPA <40 mmHg, n=168), 2nd — with moderate PH (SPPA 40-55 mmHg, n=101), 3rd — with severe PH (SPPA >55 mmHg, n=19). Results. Increase of SPPA was found in 120 (41,7[%]) patients: moderate PA — in 101 (35,1[%]), severe PH — 19 (6,6[%]). It was shown that the presence and severity of PH do increase the severity of clinical signs of COPD, hemodynamic disorders, increase the rate of repeat
Авдеев С. Н. Сергей Николаевич 1968-
Гайнитдинова В. В. Вилия Вилевна 1975-
Царева Н. А. Наталья Анатольевна 1972-
Мержоева З. М. Замира Магомедовна 1977-
Avdeev S. N. Sergej Nikolaevich 1968-
Gaynitdinova V. V. Viliya Vilevna 1975-
Tsareva N. A. Natal`ya Anatolyevna 1972-
Merzhoeva Z. M. Zamira Magomedovna 1977-
Influence of pulmonary hypertension on clinical course and prognosis of patients with chronic obstructive pulmonary disease
Текст визуальный непосредственный
Российский кардиологический журнал
ООО "Силицея-Полиграф"
Т. 23, Вып. 6 С. 173-178
2018
Статья
Chronic obstructive pulmonary disease Clinical presentation Hemodynamic disorders Mortality Pulmonary hypertension Rehospitalization predictors Survival rate
amino terminal telopeptide C reactive protein fibrinogen natriuretic peptide type C derivative adult Article body mass chronic obstructive lung disease clinical evaluation clinical feature controlled study disease course disease exacerbation disease severity dyspnea female fibrinogen blood level heart right atrium heart size hemodynamics hospital mortality hospital readmission hospitalization human major clinical study male middle aged mortality rate prognosis protein blood level pulmonary artery pulmonary hypertension smoking survival rate systolic blood pressure
Aim. Evaluation of clinical specifics, predictors of repeat hospitalizations and mortality in chronic obstructive pulmonary disease (COPD) patients according to pulmonary hypertension (PH) severity grade. Material and methods. To the study, 288 COPD patients included (II-IV severity grade, GOLD 2016; males 276, females 12; mean age 59,5±9,27 y. o., smoking 23,1±11,42 pack/years; 2,4±0,89 exacerbations annually, body mass index (BMI) 27,2±12,06 kg/m2). According to the presence and grade of systolic pressure increase in pulmonary artery (SPPA) the patients were selected to three groups: 1st — with no PH (SPPA <40 mmHg, n=168), 2nd — with moderate PH (SPPA 40-55 mmHg, n=101), 3rd — with severe PH (SPPA >55 mmHg, n=19). Results. Increase of SPPA was found in 120 (41,7[%]) patients: moderate PA — in 101 (35,1[%]), severe PH — 19 (6,6[%]). It was shown that the presence and severity of PH do increase the severity of clinical signs of COPD, hemodynamic disorders, increase the rate of repeat