Application of bacterial therapeutic vaccine Immunovac-VP4 in the treatment of pollinosis
Костинов М. П., Поддубикова А. М., Магаршак О. О., Поддубиков А. В.
Терапевтический архив
Т. 90, Вып. 3, С. 16-20
Опубликовано: 2018
Тип ресурса: Статья
DOI:10.26442/terarkh201890316-20
Аннотация:
In-depth study of the function and structure of the lymphoid tissue of the gastrointestinal tract and respiratory tract opens wide opportunities for the use of mucosal vaccines to improve immunity to various infectious agents. One such drug is The immunovac-VP4 vaccine containing pathogen-associated molecular structures (PAMSs) of microorganisms. They are the antigens of Klebsiella pneumoniae, Proteus vulgaris, Escherichia coli, Staphylococcus aureus. Discovered in many studies and experiments, the ability of the vaccine to induce innate immunity provides opportunities for prevention and treatment of both infections and allergic diseases, because it promotes the switching of Th2 immune response to Th1. The aim of the study was to study the effectiveness of the complex use of bacterial therapeutic vaccine Immunovac-VP4 and allergen-specific immune therapy (ASIT) in pollinosis in children and adults. Materials and methods. Bacterial therapeutic vaccine Immunovac-VP4 was used annually, na
Ключевые слова:
Allergen-specific immunotherapy; Bacterial vaccines; Desensitization; Immunovac-VP4; PAMPs; Pollinosis
allergen; bacterial vaccine; adult; child; desensitization; human; immunology; pollen allergy; treatment outcome; Adult; Allergens; Bacterial Vaccines; Child; Desensitization, Immunologic; Humans; Rhinitis, Allergic, Seasonal; Treatment Outcome
Язык текста: Русский
ISSN: 2309-5342
Костинов М. П. Михаил Петрович 1956-
Поддубикова А. М.
Магаршак О. О.
Поддубиков А. В.
Kostinov M. P. Mikhail Petrovich 1956-
Poddubikova A. M.
Magarshak O. O.
Poddubikov A. V.
Application of bacterial therapeutic vaccine Immunovac-VP4 in the treatment of pollinosis
Текст визуальный непосредственный
Терапевтический архив
Медицинское маркетинговое агентство "МедиаМедика"
Т. 90, Вып. 3 С. 16-20
2018
Статья
Allergen-specific immunotherapy Bacterial vaccines Desensitization Immunovac-VP4 PAMPs Pollinosis
allergen bacterial vaccine adult child desensitization human immunology pollen allergy treatment outcome Adult Allergens Bacterial Vaccines Child Desensitization, Immunologic Humans Rhinitis, Allergic, Seasonal Treatment Outcome
In-depth study of the function and structure of the lymphoid tissue of the gastrointestinal tract and respiratory tract opens wide opportunities for the use of mucosal vaccines to improve immunity to various infectious agents. One such drug is The immunovac-VP4 vaccine containing pathogen-associated molecular structures (PAMSs) of microorganisms. They are the antigens of Klebsiella pneumoniae, Proteus vulgaris, Escherichia coli, Staphylococcus aureus. Discovered in many studies and experiments, the ability of the vaccine to induce innate immunity provides opportunities for prevention and treatment of both infections and allergic diseases, because it promotes the switching of Th2 immune response to Th1. The aim of the study was to study the effectiveness of the complex use of bacterial therapeutic vaccine Immunovac-VP4 and allergen-specific immune therapy (ASIT) in pollinosis in children and adults. Materials and methods. Bacterial therapeutic vaccine Immunovac-VP4 was used annually, na