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One-dimensional mathematical model-based automated assessment of fractional flow reserve in a patient with silent myocardial ischemia

Gognieva D. G., Gamilov T. M., Pryamonosov R. A., Betelin V., Ternovoj S. K., Serova N. S., Abugov S. A., Shhekochikhin D. Yu., Mitina Y., El-Manaa H., Kopy'lov F. Yu.
American Journal of Case Reports
Vol.19, P. 724-728
Опубликовано: 2018
Тип ресурса: Статья

DOI:10.12659/AJCR.908449

Аннотация:
Objective: Unusual setting of medical care Background: Noninvasive assessment of the fractional flow reserve (FFR) in patients with coronary artery disease plays an important role in determining the need for revascularization. It is particularly relevant for patients with a borderline stenoses and painless myocardial ischemia. Our article describes the first clinical experience in the Russian Federation of using an automated method of noninvasive assessment of the fractional flow reserve (FFRct) with a one-dimensional (1-D) mathematical model in a patient with painless myocardial ischemia. Case Report: A 58-year-old male patient who underwent stent implantation in the left circumflex coronary artery (LCX) due to an acute non-ST-elevation posterior myocardial infarction had borderline stenoses of the left anterior descending artery (LAD). After stent implantation, there were no relapse angina symptoms on drug treatment, and according to our examination guideline for patients with border
Ключевые слова:
Coronary artery disease; Fractional flow reserve; Models; Myocardial; Theoretical
adult; Article; automation; borderline state; case report; clinical article; clinical practice; coronary artery disease; exercise test; fractional flow reserve; heart muscle ischemia; heart muscle revascularization; human; left anterior descending coronary artery; male; mathematical model; medical care; multidetector computed tomography; non invasive measurement; non ST segment elevation myocardial infarction; pathophysiology; percutaneous coronary intervention; rating scale; silent myocardial ischemia; treadmill test; blood vessel transplantation; coronary angiography; heart muscle ischemia; laboratory automation; middle aged; pathophysiology; physiology; stent; theoretical model; Automation, Laboratory; Blood Vessel Prosthesis Implantation; Coronary Angiography; Fractional Flow Reserve, Myocardial; Humans; Male; Middle Aged; Models, Theoretical; Myocardial Ischemia; Percutaneous Coronary Intervention; Stents
Язык текста: Английский
ISSN: 1941-5923
Gognieva D. G. Dar`ya Gennadievna 1990-
Gamilov T. M. Timur Mudarisovich 1988-
Pryamonosov R. A. Roman Aleksandrovich 1992-
Betelin V.
Ternovoj S. K. Sergej Konstantinovich 1948-
Serova N. S. Natal`ya Sergeevna 1979-
Abugov S. A. Sergej Aleksandrovich 0001-
Shhekochikhin D. Yu. Dmitrij Yuryevich 1985-
Mitina Y.
El-Manaa H.
Kopy'lov F. Yu. Filipp Yuryevich 1976-
Гогниева Д. Г. Дарья Геннадиевна 1990-
Гамилов Т. М. Тимур Мударисович 1988-
Прямоносов Р. А. Роман Александрович 1992-
Бетелин В.
Терновой С. К. Сергей Константинович 1948-
Серова Н. С. Наталья Сергеевна 1979-
Абугов С. А. Сергей Александрович 0001-
Щекочихин Д. Ю. Дмитрий Юрьевич 1985-
Митина Y.
Ел-Манаа Х.
Копылов Ф. Ю. Филипп Юрьевич 1976-
One-dimensional mathematical model-based automated assessment of fractional flow reserve in a patient with silent myocardial ischemia
Текст визуальный непосредственный
American Journal of Case Reports
Vol.19 P. 724-728
2018
Статья
Coronary artery disease Fractional flow reserve Models Myocardial Theoretical
adult Article automation borderline state case report clinical article clinical practice coronary artery disease exercise test fractional flow reserve heart muscle ischemia heart muscle revascularization human left anterior descending coronary artery male mathematical model medical care multidetector computed tomography non invasive measurement non ST segment elevation myocardial infarction pathophysiology percutaneous coronary intervention rating scale silent myocardial ischemia treadmill test blood vessel transplantation coronary angiography heart muscle ischemia laboratory automation middle aged pathophysiology physiology stent theoretical model Automation, Laboratory Blood Vessel Prosthesis Implantation Coronary Angiography Fractional Flow Reserve, Myocardial Humans Male Middle Aged Models, Theoretical Myocardial Ischemia Percutaneous Coronary Intervention Stents
Objective: Unusual setting of medical care Background: Noninvasive assessment of the fractional flow reserve (FFR) in patients with coronary artery disease plays an important role in determining the need for revascularization. It is particularly relevant for patients with a borderline stenoses and painless myocardial ischemia. Our article describes the first clinical experience in the Russian Federation of using an automated method of noninvasive assessment of the fractional flow reserve (FFRct) with a one-dimensional (1-D) mathematical model in a patient with painless myocardial ischemia. Case Report: A 58-year-old male patient who underwent stent implantation in the left circumflex coronary artery (LCX) due to an acute non-ST-elevation posterior myocardial infarction had borderline stenoses of the left anterior descending artery (LAD). After stent implantation, there were no relapse angina symptoms on drug treatment, and according to our examination guideline for patients with border