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Results of experimental studies of the children’s axial pump «Don-3»

Иткин Г. П., Дмитриева О. Y., Бучнев А. С., Дробyшев А. А., Кулешов А. П., Волкова А. В., Халилулин Т. А.
Вестник трансплантологии и искусственных органов
Т. 20, Вып. 2, С. 61-68
Опубликовано: 2018
Тип ресурса: Статья

DOI:10.15825/1995-1191-2018-2-61-68

Аннотация:
Aim. To evaluate the functioning of an implantable pediatric axial pump «DON-3» for bypassing the left ventricle of the heart in experiments on sheep. Materials and methods. Five sheeps at the age of 12–18 months performed paracorporeal installation of the children’s axial pump «DON-3» according to the scheme «left ventricle – aorta». Results. A technique was developed and 5 chronic experiments were conducted on sheep to assess the model of the children’s axial pump «DON-3». The duration of the experiments in this series averaged 9 ± 5 days. The main indicators of hemodynamics, acid-base balance were within the norm. Conducted morphological and histological studies of the kidneys, liver and lungs did not reveal the presence of zones of ischemia and thromboembolism. Conclusion. The results of this series of experiments showed satisfactory results, suggesting further research on the development of prototypes of a pediatric pump for clinical practice. © 2018 Russian Transplant Society. Al
Ключевые слова:
Children’s axial pump; Mechanical support of blood circulation; Pumps of non-pulsating flow; Terminal heart failure
Язык текста: Русский
ISSN: 2412-6160
Иткин Г. П.
Дмитриева О. Y. О.Ю.
Бучнев А. С.
Дробyшев А. А.
Кулешов А. П.
Волкова А. В.
Халилулин Т. А.
Itkin G. P.
Dmitrieva O. Y. O.Yu.
Buchnev A. S.
Drobyshev A. A.
Kuleshov A. P.
Volkova A. V.
Halilulin T. A.
Results of experimental studies of the children’s axial pump «Don-3»
Текст визуальный непосредственный
Вестник трансплантологии и искусственных органов
Федеральный научный центр трансплантологии и искусственных органов им. академика В.И. Шумакова
Т. 20, Вып. 2 С. 61-68
2018
Статья
Children’s axial pump Mechanical support of blood circulation Pumps of non-pulsating flow Terminal heart failure
Aim. To evaluate the functioning of an implantable pediatric axial pump «DON-3» for bypassing the left ventricle of the heart in experiments on sheep. Materials and methods. Five sheeps at the age of 12–18 months performed paracorporeal installation of the children’s axial pump «DON-3» according to the scheme «left ventricle – aorta». Results. A technique was developed and 5 chronic experiments were conducted on sheep to assess the model of the children’s axial pump «DON-3». The duration of the experiments in this series averaged 9 ± 5 days. The main indicators of hemodynamics, acid-base balance were within the norm. Conducted morphological and histological studies of the kidneys, liver and lungs did not reveal the presence of zones of ischemia and thromboembolism. Conclusion. The results of this series of experiments showed satisfactory results, suggesting further research on the development of prototypes of a pediatric pump for clinical practice. © 2018 Russian Transplant Society. Al