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The risk of osteoporotic fractures in patients with rheumatoid arthritis: Results of the program «osteoscreening Russia»

Никитинскайа О. А., Торопцова Н. В., Демин Н. В., Феклистов А. Y., Насонов Е. Л.
Научно-практическая ревматология
Т. 56, Вып. 3, С. 310-315
Опубликовано: 2018
Тип ресурса: Статья

DOI:10.14412/1995-4484-2018-310-315

Аннотация:
Rheumatoid arthritis (RA) and the use of glucocorticoids (GCs) are proven risk factors for osteoporosis (OP) and osteoporotic fractures (OPF). There are also other reasons for increased fracture risk in RA. Objective: to determine the rate of RA in an epidemiological sample of persons aged 50 years and older and to identify those in need of antiosteoporotic therapy among the patients with RA in order to prevent OPF. Subjects and methods. The epidemiological sample included 18,018 people aged 50 years and older (13,941 women and 4,077 men; mean age, 62±10 years). The survey consisted of a unified questionnaire, measurement of daily dietary calcium intake, and calculation of a 10-year fracture risk using the FRAX® algorithm. Results and discussion. The prevalence of RA in the epidemiological population sample aged 50 years and older was 1.7[%] (1.9[%] in women and 1.2[%] in men; p=0.0047). The mean FRAX® values for major OPF in RA patients were significantly higher than those in non-RA individ
Ключевые слова:
Calcium intake; FRAX®; Osteoporosis; Peripheral densitometry; Rheumatoid arthritis; Risk fracture factors
Язык текста: Русский
ISSN: 1995-4492
Никитинскайа О. А.
Торопцова Н. В.
Демин Н. В.
Феклистов А. Y. А.Ю.
Насонов Е. Л. Евгений Львович 1948-
Nikitinskaya O. A.
Toroptsova N. V.
Demin N. V.
Feklistov A. Y. A.Yu.
Nasonov E. L. Evgenij L`vovich 1948-
The risk of osteoporotic fractures in patients with rheumatoid arthritis: Results of the program «osteoscreening Russia»
Текст визуальный непосредственный
Научно-практическая ревматология
ИМА-Пресс
Т. 56, Вып. 3 С. 310-315
2018
Статья
Calcium intake FRAX® Osteoporosis Peripheral densitometry Rheumatoid arthritis Risk fracture factors
Rheumatoid arthritis (RA) and the use of glucocorticoids (GCs) are proven risk factors for osteoporosis (OP) and osteoporotic fractures (OPF). There are also other reasons for increased fracture risk in RA. Objective: to determine the rate of RA in an epidemiological sample of persons aged 50 years and older and to identify those in need of antiosteoporotic therapy among the patients with RA in order to prevent OPF. Subjects and methods. The epidemiological sample included 18,018 people aged 50 years and older (13,941 women and 4,077 men; mean age, 62±10 years). The survey consisted of a unified questionnaire, measurement of daily dietary calcium intake, and calculation of a 10-year fracture risk using the FRAX® algorithm. Results and discussion. The prevalence of RA in the epidemiological population sample aged 50 years and older was 1.7[%] (1.9[%] in women and 1.2[%] in men; p=0.0047). The mean FRAX® values for major OPF in RA patients were significantly higher than those in non-RA individ