Рациональная фармакотерапия в кардиологии
Т. 15, Вып. 4, С. 568-577
Аннотация:
The review presents the important problem of resistant hypertension. Its real prevalence is unknown. According to population studies and meta-analyzes of clinical studies, the prevalence of this most severe form of hypertension reaches 12-15[%] in the general population and 15-18[%] in clinical cohorts. Over the past decades, an increase in its frequency among patients with hypertension has been noted. Based on the results of large-scale studies, risk factors are detected that allow to assess the risk for the resistance to antihypertensive drugs. Adherence to ongoing antihypertensive therapy is crucial to addressing the issue of hypertension resistance; there are acceptable ways to evaluate it in clinical practice. The review discusses the most common mistakes in the choice of therapy, which can cause resistance to antihypertensive treatment, namely irrational drug combinations, insufficient dosage of the drug, and the use of non-prolonged forms of drugs. The latest recommendations for the
Ключевые слова:
Adherence; Amlodipine; Fixed combination; Indapamide; Lisinopril; Resistant hypertension; Spironolactone
amlodipine; diuretic agent; spironolactone; antihypertensive therapy; Article; clinical practice; human; population; resistant hypertension; risk factor
Подзолков В. И. Валерий Иванович 1948-
Брагина А. Е. Анна Евгеньевна 1973-
Осадчий К. К. Константин Константинович 0001-
Podzolkov V. I. Valerij Ivanovich 1948-
Bragina A. E. Anna Evgenyevna 1973-
Osadchij K. K. Konstantin Konstantinovich 0001-
Resistant hypertension: Questions and contemporary answers [Резистентная гипертензия: вопросы и современные ответы]
Текст визуальный непосредственный
Рациональная фармакотерапия в кардиологии
Столичная издательская компания
Т. 15, Вып. 4 С. 568-577
2019
Статья
Adherence Amlodipine Fixed combination Indapamide Lisinopril Resistant hypertension Spironolactone
amlodipine diuretic agent spironolactone antihypertensive therapy Article clinical practice human population resistant hypertension risk factor
The review presents the important problem of resistant hypertension. Its real prevalence is unknown. According to population studies and meta-analyzes of clinical studies, the prevalence of this most severe form of hypertension reaches 12-15[%] in the general population and 15-18[%] in clinical cohorts. Over the past decades, an increase in its frequency among patients with hypertension has been noted. Based on the results of large-scale studies, risk factors are detected that allow to assess the risk for the resistance to antihypertensive drugs. Adherence to ongoing antihypertensive therapy is crucial to addressing the issue of hypertension resistance; there are acceptable ways to evaluate it in clinical practice. The review discusses the most common mistakes in the choice of therapy, which can cause resistance to antihypertensive treatment, namely irrational drug combinations, insufficient dosage of the drug, and the use of non-prolonged forms of drugs. The latest recommendations for the