Significance and management of incidentally diagnosed metastatic papillary thyroid carcinoma in cervical lymph nodes in neck dissection specimens
Mandapathil M., Lennon P., Ganly I., Patel S. G., Sha D. P.
Head & Neck: journal for the sciences and specialities of the head and neck
Vol.41, Issue11, P. 3783-3787
Опубликовано: 2019
Тип ресурса: Статья
Аннотация:
Background: The management of patients with incidentally discovered metastatic thyroid cancer in cervical lymph nodes in neck dissection specimens for other pathologies is unclear. Methods: Retrospective review of neck dissection specimens for nonthyroid malignancy during a 30-year period was undertaken to identify incidental metastatic papillary thyroid cancer (PTC). Results: Twenty-six patients had an incidental finding of PTC in lymph node(s) in neck dissection specimens. Subsequent ultrasound of the thyroid showed nodules in 20 patients. Eleven (42[%]) underwent total thyroidectomy, 1 (4[%]) had a lobectomy, and 14 (54[%]) were kept under active surveillance only. At a median follow-up of 48 months (range 10-189 months), all patients who had undergone surgery and those under surveillance were free of PTC recurrence. Conclusion: Evaluation for detection of a primary thyroid tumor is essential in all patients with incidentally discovered metastatic PTC. Decision regarding surgery or survei
Ключевые слова:
aberrant thyroid tissue; incidental finding; neck metastases; occult metastases; papillary thyroid cancer
radioactive iodine; adenocarcinoma; advanced cancer; aged; Article; cancer epidemiology; cancer staging; cervical lymph node metastasis; cohort analysis; female; human; human tissue; incidental finding; lobectomy; major clinical study; male; melanoma; mouth cancer; neck dissection; nonthyroid primary tumor; oropharynx cancer; postoperative care; primary tumor; priority journal; recurrent disease; salivary adenocarcinoma; salivary gland tumor; thyroid nodule; thyroid papillary carcinoma; thyroidectomy; tonsil cancer
Язык текста: Английский
ISSN: 1097-0347
Mandapathil M.
Lennon P.
Ganly I.
Patel S. G.
Sha D. P. Dzhatin Premanand 1940-
Мандапатхил М.
Леннон П.
Ганлy И.
Пател С. Г.
Ша Д. П. Джатин Премананд 1940-
Significance and management of incidentally diagnosed metastatic papillary thyroid carcinoma in cervical lymph nodes in neck dissection specimens
Текст визуальный непосредственный
Head & Neck: journal for the sciences and specialities of the head and neck
John Wiley & Sons, Inc.
Vol.41, Issue11 P. 3783-3787
2019
Статья
aberrant thyroid tissue incidental finding neck metastases occult metastases papillary thyroid cancer
radioactive iodine adenocarcinoma advanced cancer aged Article cancer epidemiology cancer staging cervical lymph node metastasis cohort analysis female human human tissue incidental finding lobectomy major clinical study male melanoma mouth cancer neck dissection nonthyroid primary tumor oropharynx cancer postoperative care primary tumor priority journal recurrent disease salivary adenocarcinoma salivary gland tumor thyroid nodule thyroid papillary carcinoma thyroidectomy tonsil cancer
Background: The management of patients with incidentally discovered metastatic thyroid cancer in cervical lymph nodes in neck dissection specimens for other pathologies is unclear. Methods: Retrospective review of neck dissection specimens for nonthyroid malignancy during a 30-year period was undertaken to identify incidental metastatic papillary thyroid cancer (PTC). Results: Twenty-six patients had an incidental finding of PTC in lymph node(s) in neck dissection specimens. Subsequent ultrasound of the thyroid showed nodules in 20 patients. Eleven (42[%]) underwent total thyroidectomy, 1 (4[%]) had a lobectomy, and 14 (54[%]) were kept under active surveillance only. At a median follow-up of 48 months (range 10-189 months), all patients who had undergone surgery and those under surveillance were free of PTC recurrence. Conclusion: Evaluation for detection of a primary thyroid tumor is essential in all patients with incidentally discovered metastatic PTC. Decision regarding surgery or survei