Аннотация:
OBJECTIVE: To compare incidence of thromboembolic and hemorrhagic complications in patients with atrial fibrillation (AF) undergoing elective surgery on different schemes of perioperative anticoagulant therapy (ACT). MATERIAL AND METHODS: There were 86 patients (56 (65.1[%]) men and 30 (34.9[%]) women, mean age was 69 (64; 78) years) with non-valvular AF who underwent elective interventions. Forty (46.5[%]) patients underwent abdominal surgery, 34 (39.5[%]) - cardiovascular procedures, 12 (14.0[%]) patients underwent surgery for malignant diseases. We have analyzed incidence of thromboembolic and hemorrhagic events and compliance of perioperative ACT modes with current international guidelines. RESULTS: Thromboembolic and hemorrhagic events developed in 14 (16.3[%]) patients. Thromboembolic complications were noted in 6 (7.0[%]) patients, hemorrhagic events - in 8 (9.3[%]) cases. Maximum complication rate was observed in case of bridge-therapy (n=12, 20.0[%]). Cancellation of ACT was followed by 2 (9.5[%]
Ключевые слова:
anticoagulant therapy; atrial fibrillation; bleeding; bridge-therapy; thromboembolic complications
anticoagulant agent; adverse event; aged; atrial fibrillation; bleeding; complication; elective surgery; female; human; male; middle aged; protocol compliance; thromboembolism; Aged; Anticoagulants; Atrial Fibrillation; Elective Surgical Procedures; Female; Guideline Adherence; Hemorrhage; Humans; Male; Middle Aged; Thromboembolism
Уддин Л. Н.
Соколова А. А. Анастасия Андреевна 1983-
Егоров А. В.
Напалков Д. А. Дмитрий Александрович 1975-
Фомин В. В. Виктор Викторович 1978-
Вычужанин Д. В. Дмитрий Викторович 1980-
Дзюндзя А. Н. Андрей Николаевич 1984-
Абдулхакимов Н. М.
Трифонова А. А. Анастасия Александровна 1996-
Uddin L. N.
Sokolova A. A. Anastasiya Andreevna 1983-
Egorov A. V.
Napalkov D. A. Dmitrij Aleksandrovich 1975-
Fomin V. V. Viktor Viktorovich 1978-
Vy'chuzhanin D. V. Dmitrij Viktorovich 1980-
Dzyundzya A. N. Andrej Nikolaevich 1984-
Abdulkhakimov N. M.
Trifonova A. A. Anastasiya Aleksandrovna 1996-
Prevention of thromboembolic and hemorrhagic events in patients with atrial fibrillation undergoing elective surgery [Profilaktika tromboémbolicheskikh i gemorragicheskikh oslozhneniĭ u patsientov s fibrilliatsieĭ predserdiĭ pri provedenii planovogo khirurgicheskogo lecheniia]
Prevention of thromboembolic and hemorrhagic events in patients with atrial fibrillation undergoing elective surgery [Profilaktika...
Текст визуальный непосредственный
Хирургия. Журнал им. Н.И. Пирогова
Издательство Медиа Сфера
Вып. 7 С. 52-57
2019
Статья
anticoagulant therapy atrial fibrillation bleeding bridge-therapy thromboembolic complications
anticoagulant agent adverse event aged atrial fibrillation bleeding complication elective surgery female human male middle aged protocol compliance thromboembolism Aged Anticoagulants Atrial Fibrillation Elective Surgical Procedures Female Guideline Adherence Hemorrhage Humans Male Middle Aged Thromboembolism
OBJECTIVE: To compare incidence of thromboembolic and hemorrhagic complications in patients with atrial fibrillation (AF) undergoing elective surgery on different schemes of perioperative anticoagulant therapy (ACT). MATERIAL AND METHODS: There were 86 patients (56 (65.1[%]) men and 30 (34.9[%]) women, mean age was 69 (64; 78) years) with non-valvular AF who underwent elective interventions. Forty (46.5[%]) patients underwent abdominal surgery, 34 (39.5[%]) - cardiovascular procedures, 12 (14.0[%]) patients underwent surgery for malignant diseases. We have analyzed incidence of thromboembolic and hemorrhagic events and compliance of perioperative ACT modes with current international guidelines. RESULTS: Thromboembolic and hemorrhagic events developed in 14 (16.3[%]) patients. Thromboembolic complications were noted in 6 (7.0[%]) patients, hemorrhagic events - in 8 (9.3[%]) cases. Maximum complication rate was observed in case of bridge-therapy (n=12, 20.0[%]). Cancellation of ACT was followed by 2 (9.5[%]